The effects of strength, aerobic, and concurrent exercise on skeletal muscle damage in rats

• Published in: Muscle & nerve Vol. 50; no. 1; pp. 79 - 86
• Main Authors: Rech, Anderson, Radaelli, Regis, De Assis, Adriano M., Fernandes, João R., Longoni, Aline, Vozari-Hampe, Magdolna M., Pinto, Ronei S., Matté, Cristiane
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2014; Wiley Subscription Services, Inc
• Subjects: Aerobiosis; Animals; Catalase - metabolism; concurrent exercise; Exercise; exercise recovery; Fluoresceins; Fluorescent Dyes; gastrocnemius; Glutathione Peroxidase - metabolism; L-Lactate Dehydrogenase - metabolism; Male; muscle damage; Muscle Strength - physiology; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - injuries; Musculoskeletal system; Oxidation-Reduction; Oxidative stress; Oxidative Stress - physiology; Physical Conditioning, Animal - physiology; Physical fitness; Rats; Rats, Wistar; Resistance Training; Rodents; Sulfhydryl Compounds - metabolism; Superoxide Dismutase - metabolism; Ultrasonography; concurrent exercise; gastrocnemius; muscle damage; exercise recovery; oxidative stress
• ISSN: 0148-639X; 1097-4598; 1097-4598
• DOI: 10.1002/mus.24091

ABSTRACT Introduction: In this study we examined oxidative stress and skeletal muscle damage resulting from acute strength, aerobic, or concurrent exercise in rats. Methods: The animals were divided into control (C), strength (SE), aerobic (AE), and combined (CE) exercise groups. They were euthanized at 3 different time‐points (6, 24, and 48 h) after acute exercise. Results: SE exercise rats had increased dichlorofluorescein oxidation at 6 h post‐exercise and decreased superoxide dismutase activity at all time‐points. Glutathione peroxidase activity and sulfhydryl levels were increased in the AE group at 48 h post‐exercise. Serum lactate dehydrogenase activity was increased in the SE and CE groups at 24 h and in the AE group at 48 h. Echo intensity was elevated at 24 h for all groups. Conclusions: Forty‐eight hours was sufficient for complete recovery from oxidative stress and muscle damage in the SE and CE groups, but not in the AE group. Muscle Nerve 50: 79–86, 2014