The impact of advanced maternal age on pregnancy outcome
Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and feta...
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| Published in | Best practice & research. Clinical obstetrics & gynaecology Vol. 70; pp. 2 - 9 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
Elsevier Ltd
01.01.2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1521-6934 1532-1932 1532-1932 |
| DOI | 10.1016/j.bpobgyn.2020.06.006 |
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| Abstract | Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and fetal outcomes. This chapter reviews and summarizes the recent publications on the impact of advanced maternal age on pregnancy outcomes.
•Advanced maternal age (AMA) leads to a decrease in fertility, increased need for ART, and increased in early fetal loss because of the impact on chromosomal and genetic disorders.•Elderly gravidae are in risk for late pregnancy maternal complications, especially hypertension-related conditions and gestational diabetes.•AMA is also related to preterm birth, fetal growth restriction, and stillbirth. |
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| AbstractList | Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and fetal outcomes. This chapter reviews and summarizes the recent publications on the impact of advanced maternal age on pregnancy outcomes.Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and fetal outcomes. This chapter reviews and summarizes the recent publications on the impact of advanced maternal age on pregnancy outcomes. Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and fetal outcomes. This chapter reviews and summarizes the recent publications on the impact of advanced maternal age on pregnancy outcomes. Advanced maternal age is becoming an increasingly relevant issue in high-income developed countries. Lower fertility, greater need for assisted reproductive therapy, and an increase in comorbidities, such as hypertension and diabetes, are some of the reasons for the rise in adverse maternal and fetal outcomes. This chapter reviews and summarizes the recent publications on the impact of advanced maternal age on pregnancy outcomes. •Advanced maternal age (AMA) leads to a decrease in fertility, increased need for ART, and increased in early fetal loss because of the impact on chromosomal and genetic disorders.•Elderly gravidae are in risk for late pregnancy maternal complications, especially hypertension-related conditions and gestational diabetes.•AMA is also related to preterm birth, fetal growth restriction, and stillbirth. |
| Author | Yogev, Yariv Attali, Emmanuel |
| Author_xml | – sequence: 1 givenname: Emmanuel surname: Attali fullname: Attali, Emmanuel – sequence: 2 givenname: Yariv surname: Yogev fullname: Yogev, Yariv email: yarivy@tlvmc.gov.il |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32773291$$D View this record in MEDLINE/PubMed |
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| Keywords | Hypertension-related disorders Intrauterine growth restriction Pregnancy outcomes Intrauterine fetal death Assisted reproductive therapy Advanced maternal age |
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| SubjectTerms | Advanced maternal age Assisted reproductive therapy Female Fertility Humans Hypertension-related disorders Intrauterine fetal death Intrauterine growth restriction Maternal Age Pregnancy Pregnancy Outcome - epidemiology Pregnancy outcomes Reproductive Techniques, Assisted |
| Title | The impact of advanced maternal age on pregnancy outcome |
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