Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis

The bidirectional communication between the central nervous system and gut microbiota, referred to as the gut-brain-axis, has been of significant interest in recent years. Increasing evidence has associated gut microbiota to both gastrointestinal and extragastrointestinal diseases. Dysbiosis and inf...

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Bibliographic Details
Published inClinics and practice Vol. 7; no. 4; p. 987
Main Authors Clapp, Megan, Aurora, Nadia, Herrera, Lindsey, Bhatia, Manisha, Wilen, Emily, Wakefield, Sarah
Format Journal Article
LanguageEnglish
Published Italy PAGEPress Scientific Publications, Pavia, Italy 15.09.2017
MDPI AG
Subjects
anxiety
Brief Report
depression
dysbiosis
gut-brain-axis
Microbiome
anxiety
depression
gut-brain-axis
Microbiome
dysbiosis
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ISSN2039-7283
2039-7275
2039-7283
DOI10.4081/cp.2017.987

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Summary:The bidirectional communication between the central nervous system and gut microbiota, referred to as the gut-brain-axis, has been of significant interest in recent years. Increasing evidence has associated gut microbiota to both gastrointestinal and extragastrointestinal diseases. Dysbiosis and inflammation of the gut have been linked to causing several mental illnesses including anxiety and depression, which are prevalent in society today. Probiotics have the ability to restore normal microbial balance, and therefore have a potential role in the treatment and prevention of anxiety and depression. This review aims to discuss the development of the gut microbiota, the linkage of dysbiosis to anxiety and depression, and possible applications of probiotics to reduce symptoms.
Bibliography:Contributions: MC initialized the concept of this literature review; MC, NA, LH, MB, EW all contributed to research, drafting, and editing of the review. SW offered guidance and editing.
ISSN:2039-7283
2039-7275
2039-7283
DOI:10.4081/cp.2017.987