The UCSC Genome Browser database: 2018 update

• Published in: Nucleic acids research Vol. 46; no. D1; pp. D762 - D769
• Main Authors: Casper, Jonathan, Zweig, Ann S, Villarreal, Chris, Tyner, Cath, Speir, Matthew L, Rosenbloom, Kate R, Raney, Brian J, Lee, Christopher M, Lee, Brian T, Karolchik, Donna, Hinrichs, Angie S, Haeussler, Maximilian, Guruvadoo, Luvina, Navarro Gonzalez, Jairo, Gibson, David, Fiddes, Ian T, Eisenhart, Christopher, Diekhans, Mark, Clawson, Hiram, Barber, Galt P, Armstrong, Joel, Haussler, David, Kuhn, Robert M, Kent, W James
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 04.01.2018
• Subjects: CRISPR-Cas Systems; Data Display; Database Issue; Databases, Genetic; Gene Regulatory Networks; Genome; Genome, Human; Humans; Molecular Sequence Annotation; Terminology as Topic; User-Computer Interface; Web Browser
• ISSN: 0305-1048; 1362-4962; 1362-4962
• DOI: 10.1093/nar/gkx1020

Abstract The UCSC Genome Browser (https://genome.ucsc.edu) provides a web interface for exploring annotated genome assemblies. The assemblies and annotation tracks are updated on an ongoing basis-12 assemblies and more than 28 tracks were added in the past year. Two recent additions are a display of CRISPR/Cas9 guide sequences and an interactive navigator for gene interactions. Other upgrades from the past year include a command-line version of the Variant Annotation Integrator, support for Human Genome Variation Society variant nomenclature input and output, and a revised highlighting tool that now supports multiple simultaneous regions and colors.