AIE Triggers the Circularly Polarized Luminescence of Atomically Precise Enantiomeric Copper(I) Alkynyl Clusters

• Published in: Angewandte Chemie International Edition Vol. 59; no. 25; pp. 10052 - 10058
• Main Authors: Zhang, Miao‐Miao, Dong, Xi‐Yan, Wang, Zhao‐Yang, Li, Hai‐Yang, Li, Shi‐Jun, Zhao, Xueli, Zang, Shuang‐Quan
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 15.06.2020; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: alkynyl ligands; Anisotropy; Biocompatibility; Chemistry; Chemistry, Multidisciplinary; chirality; Circular polarization; circularly polarized luminescence; cluster compound; Copper; Crystallization; Crystals; Luminescence; Metal clusters; Physical Sciences; Room temperature; Science & Technology; Single crystals; PHOTOLUMINESCENCE; chirality; cluster compound; COMPLEXES; SILVER; circularly polarized luminescence; AU-I; NANOPARTICLES; GOLD CLUSTERS; METAL NANOCLUSTERS; LIGANDS; AGGREGATION-INDUCED EMISSION; copper; alkynyl ligands
• ISSN: 1433-7851; 1521-3773; 1521-3773
• DOI: 10.1002/anie.201908909

Atomically precise enantiomeric metal clusters are scarce, and copper(I) alkynyl clusters with intense circularly polarized luminescence (CPL) responses have not been reported. A pair of chiral alkynyl ligands, (R/S)‐2‐diphenyl‐2‐hydroxylmethylpyrrolidine‐1‐propyne (abbreviated as R/S‐DPM) we successfully prepared and single crystals were characterized of optically pure enantiomeric pair of atomically‐precise copper(I) clusters, [Cu14(R/S‐DPM)8](PF6)6 (denoted as R/S‐Cu14), which feature bright red luminescence and CPL with a high luminescence anisotropy factor (glum). A dilute solution containing R/S‐Cu14 was nonluminescent and CPL inactive at room temperature. Crystallization‐ and aggregation‐induced emission (CIE and AIE, respectively) contribute to the triggering of the CPL of R/S‐Cu14 in the crystalline and aggregated states. Their AIE behavior and good biocompatibility indicated applications of these copper(I) clusters in cell imaging in HeLa and NG108‐15 cells. Atomically precise chiral CuI alkynyl nanoclusters R/S‐Cu14 with inherent chirality were synthesized for the first time. Crystallization‐ and aggregation‐induced emission (CIE and AIE, respectively) trigger circularly polarized luminescence (CPL) with an unprecedented luminescence anisotropy factor (glum).