Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes

• Published in: Journal of Virology Vol. 80; no. 10; pp. 4717 - 4728
• Main Authors: Goonetilleke, Nilu, Moore, Stephen, Dally, Len, Winstone, Nicola, Cebere, Inese, Mahmoud, Abdul, Pinheiro, Susana, Gillespie, Geraldine, Brown, Denise, Loach, Vanessa, Roberts, Joanna, Guimaraes-Walker, Ana, Hayes, Peter, Loughran, Kelley, Smith, Carole, De Bont, Jan, Verlinde, Carl, Vooijs, Danii, Schmidt, Claudia, Boaz, Mark, Gilmour, Jill, Fast, Pat, Dorrell, Lucy, Hanke, Tomas, McMichael, Andrew J.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.05.2006
• Subjects: AIDS Vaccines - genetics; AIDS Vaccines - immunology; Amino Acid Sequence; Biological and medical sciences; CD8-Positive T-Lymphocytes - cytology; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - metabolism; Cell Proliferation; Cells, Cultured; Double-Blind Method; Epitopes, T-Lymphocyte - immunology; Epitopes, T-Lymphocyte - metabolism; Fundamental and applied biological sciences. Psychology; Gene Products, gag - immunology; Gene Products, gag - metabolism; Genetic Vectors; HIV Infections - prevention & control; HIV-1 - genetics; HIV-1 - immunology; Human viral diseases; Humans; Immunization, Secondary; Infectious diseases; Lymphocyte Activation - immunology; Medical sciences; Microbiology; Miscellaneous; Molecular Sequence Data; Vaccines and Antiviral Agents; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies; Vaccines, DNA - genetics; Vaccines, DNA - immunology; Vaccines, Synthetic - genetics; Vaccines, Synthetic - immunology; Vaccinia virus - genetics; Vaccinia virus - immunology; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virology; Cell proliferation; Immunopathology; Chordopoxvirinae; Antigenic determinant; Microbiology; HIV-1 virus; Orthopoxvirus; Retroviridae; AIDS; Vaccine; Immune deficiency; Lentivirus; Virology; Infection; Virus; Vaccinia virus; Poxviridae; Viral disease; T-Lymphocyte; Human immunodeficiency virus; Vector
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.80.10.4717-4728.2006

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