Bi38-3 is a novel CD38/CD3 bispecific T-cell engager with low toxicity for the treatment of multiple myeloma
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Published in | Haematologica (Roma) Vol. 106; no. 4; pp. 1193 - 1197 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Italy
Fondazione Ferrata Storti
01.04.2021
Ferrata Storti Foundation |
Subjects | |
Online Access | Get full text |
ISSN | 0390-6078 1592-8721 1592-8721 |
DOI | 10.3324/haematol.2019.242453 |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Correspondence-1 content type line 23 Disclosures: AA has received funds from Servier. Some of the work described in this letter is covered by a patent (international patent application number PCT/EP2020/070057). Contributions: MF, CM-C and JCB designed the study; MF and CM-C performed all the experiments; AB provided the anti-CD38 hybridoma; AA and NR contributed to the functional assay; EN and CC performed the mouse studies; AT, JPF and BA provided samples from patients with multiple myeloma; MF, CM-C and JCB interpreted the data, designed the figures, and drafted the manuscript. |
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ISSN: | 0390-6078 1592-8721 1592-8721 |
DOI: | 10.3324/haematol.2019.242453 |