Combining Calcium Hydroxylapatite and Hyaluronic Acid Fillers for Aesthetic Indications: Efficacy of an Innovative Hybrid Filler

• Published in: Aesthetic plastic surgery Vol. 46; no. 1; pp. 373 - 381
• Main Authors: Fakih-Gomez, Nabil, Kadouch, Jonathan
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2022; Springer Nature B.V
• Subjects: Adult; Aesthetics; Calcium; Cosmetic Techniques; Dermal Fillers - adverse effects; Durapatite - adverse effects; Esthetics; Female; Humans; Hyaluronic acid; Hyaluronic Acid - adverse effects; Hydroxyapatite; Medicine; Medicine & Public Health; Middle Aged; Original; Original Article; Otorhinolaryngology; Plastic Surgery; Retrospective Studies; Skin Aging; Young Adult; Calcium hydroxylapatite; Effectiveness; Fillers; Premixing; Hybrid; Hyaluronic acid; Radiesse
• ISSN: 0364-216X; 1432-5241; 1432-5241
• DOI: 10.1007/s00266-021-02479-x

Background Limited data are available describing effectiveness of combining the use of calcium hydroxylapatite (CaHA) and hyaluronic acid (HA). Methods The authors performed a retrospective chart review of patients injected with a premixed combination of CaHA and a cohesive polydensified matrix (CPM ® ) HA (CaHA:CPM-HA ) in the authors’ aesthetic practices. The midface and lower face were injected. Patients’ records were evaluated, and treatment results were scored using the Merz Aesthetics Scale for the jawline ® (clinician rated, CR-MASJ). Adverse events were recorded. Results A total of 41 patients were included, all females with a mean age of 47.5 years (range 21–63 years). The mean CR-MASJ score improved from 2.12 at baseline to 0.68 at t = 3 months (SD = 0.69, 95% CI 1.28–1.60) and 1.27 at t = 12 months (SD = 0.74, 95% CI 0.43–0.74). 100% of the subjects had experienced a ≥1-point improvement in CR-MASJ score at t = 3 months, versus 85% at t = 12 months. No adverse events were reported. Conclusion The results of this study support the volumizing and lifting potential of the hybrid mix CaHA:CPM-HA for treatment of cheeks and jawline. Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .