Successful pregnancy in a woman with Herlyn-Werner-Wunderlich syndrome: A case report and literature review

• Published in: Case reports in women's health Vol. 43; p. e00647
• Main Authors: Tuqan, Anas R., Salahaldin, Rayan R., Abubaker, Mais E., Zaben, Basel A., Barabrah, Anas M., Rayyan, Mohammad H., Jaber, Saadeh S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2024; Elsevier
• Subjects: Case report; Herlyn-Werner-Wunderlich syndrome; Obstructed Hemivagina; Renal agenesis; Uterine Didelphys; Obstructed Hemivagina; Case report; Uterine Didelphys; Renal agenesis; Herlyn-Werner-Wunderlich syndrome
• ISSN: 2214-9112; 2214-9112
• DOI: 10.1016/j.crwh.2024.e00647

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital condition characterized by renal agenesis, uterine didelphys, and obstructed hemivagina. This report presents the case of a 19-year-old woman who reported lower abdominal pain and offensive vaginal discharge. Imaging revealed a didelphys uterus, two vaginas, two cervixes, hematocolpos, and an absent right kidney. Surgical intervention involved draining the hematocolpos and excising the uterine septum. After surgery, the patient successfully conceived and had a full-term pregnancy, delivering via cesarean section without complications. This case highlights the importance of early diagnosis and surgical management in preventing complications such as endometriosis and infertility. Prompt recognition and treatment are crucial for preserving fertility in patients with HWW syndrome. •Herlyn-Werner-Wunderlich syndrome involves renal agenesis, uterine didelphys, and obstructed hemivagina.•Ultrasonography and MRI are key in diagnosing Herlyn-Werner-Wunderlich syndrome.•Early detection and treatment of HWW syndrome are vital for fertility preservation and avoiding complications.