Enhanced radiographic visualization of resorbable foils for orbital floor reconstruction: A proof of principle

• Published in: Journal of cranio-maxillo-facial surgery Vol. 46; no. 9; pp. 1533 - 1538
• Main Authors: Doll, Christian, Thieme, Nadine, Schönmuth, Stefanie, Voss, Jan Oliver, Nahles, Susanne, Beck-Broichsitter, Benedicta, Heiland, Max, Raguse, Jan-Dirk
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.09.2018
• Subjects: Cadaver; Calcium Phosphates - chemistry; Cone-Beam Computed Tomography; Durapatite - chemistry; Humans; Lactic Acid - chemistry; Magnesium - chemistry; Materials Testing; Orbital floor fracture; Orbital Fractures - diagnostic imaging; Orbital Fractures - surgery; Orbital Implants; Polyesters - chemistry; Proof of Concept Study; Radiopaque; Reconstruction; Resorbable foil; Surgical Mesh; Tomography, X-Ray Computed; Reconstruction; Orbital floor fracture; Resorbable foil; Radiopaque
• ISSN: 1010-5182; 1878-4119; 1878-4119
• DOI: 10.1016/j.jcms.2018.05.045

Despite the advantages and broad applications of alloplastic resorbable implants, postoperative radiological control is challenging due to its radiolucency. The aim of the present study was to evaluate the radiographic visibility of newly developed materials for orbital floor reconstruction. The radiographic visibility of four different material combinations consisting of poly-(L-lactic acid)/poly-glycolic acid (PLLA/PGA) or poly(D,L-lactic acid) (PDLLA) enriched with magnesium (Mg), hydroxyapatite (HA) or β-tricalcium phosphate (β-TCP) with various layers of thicknesses (0.3, 0.6, and 1 mm), surgically placed above the orbital floor of a human head specimen, was evaluated using computed tomography (CT) and cone beam computed tomography (CBCT). The visibility was rated on a scale of 0–10 in CT/CBCT and by Hounsfield Units in CT for each subject. All of the materials were clearly detectable in CT scans. Visibility was significantly higher (p < 0.001) in the standard soft tissue window (mean score: 7.3, ranging from 2 to 10) in comparison to the standard bone window (mean score: 5.2, ranging from 1 to 10). In CBCT (mean score: 3.3, ranging from 0 to 7), there was significantly lower but still sufficient visibility of the materials compared to the CT soft tissue window (p < 0.001) and CT bone window (p < 0.001). Comparing the different materials' visibility among the group of same layer thicknesses with each other, in the majority of cases, PDLLA enriched with β-TCP appeared to be most visible in both CT and CBCT. The incorporation of radiopaque elements to PLLA/PGA and PDLLA polymers is a promising strategy to improve their visibility in CT and CBCT. Our data suggest that the reconstruction of the orbital floor with these new materials could provide an advantageous postoperative radiographic control.