Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy

• Published in: The New England journal of medicine Vol. 381; no. 8; pp. 739 - 748
• Main Authors: Panza, Julio A, Ellis, Alicia M, Al-Khalidi, Hussein R, Holly, Thomas A, Berman, Daniel S, Oh, Jae K, Pohost, Gerald M, Sopko, George, Chrzanowski, Lukasz, Mark, Daniel B, Kukulski, Tomasz, Favaloro, Liliana E, Maurer, Gerald, Farsky, Pedro S, Tan, Ru-San, Asch, Federico M, Velazquez, Eric J, Rouleau, Jean L, Lee, Kerry L, Bonow, Robert O
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 22.08.2019
• Subjects: Aged; Cardiomyopathy; Cardiovascular disease; Computed tomography; Coronary artery; Coronary Artery Bypass; Coronary vessels; Death; Echocardiography; Echocardiography, Stress; Female; Follow-Up Studies; Heart; Heart - diagnostic imaging; Heart - physiology; Heart diseases; Heart failure; Heart surgery; Humans; Hypotheses; Incidence; Ischemia; Kaplan-Meier Estimate; Laboratories; Male; Medical prognosis; Middle Aged; Myocardial Ischemia - mortality; Myocardial Ischemia - physiopathology; Myocardial Ischemia - surgery; Myocardium; NMR; Nuclear magnetic resonance; Patients; Proportional Hazards Models; Prospective Studies; Stroke Volume; Tomography; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Ventricle; Ventricular Function, Left
• ISSN: 0028-4793; 1533-4406; 1533-4406
• DOI: 10.1056/NEJMoa1807365

The role of myocardial viability assessment in identifying patients with ischemic cardiomyopathy who will benefit from surgical revascularization is controversial. This study assessed myocardial viability and its relationship to long-term outcomes in 601 patients with ischemic cardiomyopathy who were assigned to surgical revascularization plus medical therapy or medical therapy alone.