Validation of Group B Borderline Resectable Pancreatic Cancer: Retrospective Analysis

Among borderline resectable pancreatic cancer (BRPC), group B BRPC patients have findings that are suggestive but not diagnostic of metastasis. In this study, we attempted to validate whether group B could truly be categorized as a borderline resectable group. We placed the BRPC patients into group...

Full description

Saved in:
Bibliographic Details
Published inGut and liver Vol. 8; no. 5; pp. 557 - 562
Main Authors Oh, Tak Geun, Chung, Moon Jae, Bang, Seungmin, Park, Seung Woo, Chung, Jae Bok, Song, Si Young, Seong, Jinsil, Kang, Chang Moo, Lee, Woo Jung, Park, Jeong Youp
Format Journal Article
LanguageEnglish
Published Korea (South) Gut and Liver 01.09.2014
Gastroenterology Council for Gut and Liver
거트앤리버 소화기연관학회협의회
Subjects
Online AccessGet full text
ISSN1976-2283
2005-1212
2005-1212
DOI10.5009/gnl13264

Cover

More Information
Summary:Among borderline resectable pancreatic cancer (BRPC), group B BRPC patients have findings that are suggestive but not diagnostic of metastasis. In this study, we attempted to validate whether group B could truly be categorized as a borderline resectable group. We placed the BRPC patients into group A or group B. The survival outcomes were compared between the groups. A total of 53 patients with pancreatic adenocarcinoma was classified as either group A or B borderline resectable. In group A, 23 (60.5%) of 38 patients underwent pancreatectomy after concurrent chemoradiotherapy or chemotherapy, but in group B, only five (33.3%) of 15 patients underwent pancreatectomy, mainly because of the progression of suspected distant metastasis. There was a significant difference in overall survival (OS) between group A and B patients (median OS, 21.2 months vs 10.2 months, respectively; p=0.007). Of the patients who underwent pancreatectomy, group B had a higher recurrence rate compared to group A (recurrence rate: 11 of 23 patients [47.8%] vs five of five patients [100%], respectively; p=0.033). This report is the first to validate the definition of BPRC. Group B had much worse outcomes, and whether group B BRPC can be categorized as BRPC together with group A is questionable.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
G704-SER000001589.2014.8.5.004
ISSN:1976-2283
2005-1212
2005-1212
DOI:10.5009/gnl13264