Severe gestational diabetes mellitus in lean dams is associated with low IL-1α levels and affects the growth of the juvenile mouse offspring

We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as c...

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Published inScientific reports Vol. 13; no. 1; pp. 1700 - 14
Main Authors Mihalovičová, Lucia, Kunšteková, Veronika, Miláček, Dávid, Janko, Jakub, Pastorek, Michal, Konečná, Barbora, Gurecká, Radana, Rausová, Zuzana, Uličná, Oľga, Celec, Peter, Šebeková, Katarína
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 30.01.2023
Nature Publishing Group
Nature Portfolio
Subjects
631/136
631/337
631/443
692/4017
692/53
Adipose tissue
Adipose tissue (brown)
Animals
Blood glucose
Deoxyribonucleic acid
Diabetes mellitus
Diabetes, Gestational - metabolism
Diet
Discriminant analysis
DNA
Factor analysis
Fast food
Female
Gestational diabetes
Granulocyte-macrophage colony-stimulating factor
Growth rate
Humanities and Social Sciences
Humans
Inflammation
Interleukin 10
Kidneys
Liver
Liver - metabolism
Male
Mice
multidisciplinary
Nutrient deficiency
Obesity - complications
Offspring
Pregnancy
Prenatal Exposure Delayed Effects - metabolism
Science
Science (multidisciplinary)
Streptozocin
Variance analysis
Online AccessGet full text
ISSN2045-2322
2045-2322
DOI10.1038/s41598-023-28903-7

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Abstract We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and parameters of the cardiometabolic status (glycemia, liver lipid content; body, organ, and fat weight) were determined. Two-factor analysis of variance indicated that the male offspring of GDM dams manifest postnatal growth retardation and lower relative kidney weight. Regardless of sex, GDM offspring manifest the lowest IL-1α levels, and other inflammatory markers showed mild and inconsistent alterations. Offspring of dams consuming the FFD displayed higher liver triacylglycerols content. The three groups of offspring showed no significant differences in glycemia and extracellular DNA. Partial least squares-discriminant analysis indicated that male GDM offspring present lower kidney, body, and brown adipose tissue weights; lower IL-1α levels, and higher concentrations of GM-CSF and IL-10 compared with their FFD counterparts. The model failed to select discriminative variables in females. In conclusion, in mice, maternal GDM in the absence of obesity adversely affects the early growth of juvenile male offspring.
AbstractList We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and parameters of the cardiometabolic status (glycemia, liver lipid content; body, organ, and fat weight) were determined. Two-factor analysis of variance indicated that the male offspring of GDM dams manifest postnatal growth retardation and lower relative kidney weight. Regardless of sex, GDM offspring manifest the lowest IL-1α levels, and other inflammatory markers showed mild and inconsistent alterations. Offspring of dams consuming the FFD displayed higher liver triacylglycerols content. The three groups of offspring showed no significant differences in glycemia and extracellular DNA. Partial least squares-discriminant analysis indicated that male GDM offspring present lower kidney, body, and brown adipose tissue weights; lower IL-1α levels, and higher concentrations of GM-CSF and IL-10 compared with their FFD counterparts. The model failed to select discriminative variables in females. In conclusion, in mice, maternal GDM in the absence of obesity adversely affects the early growth of juvenile male offspring.
We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and parameters of the cardiometabolic status (glycemia, liver lipid content; body, organ, and fat weight) were determined. Two-factor analysis of variance indicated that the male offspring of GDM dams manifest postnatal growth retardation and lower relative kidney weight. Regardless of sex, GDM offspring manifest the lowest IL-1α levels, and other inflammatory markers showed mild and inconsistent alterations. Offspring of dams consuming the FFD displayed higher liver triacylglycerols content. The three groups of offspring showed no significant differences in glycemia and extracellular DNA. Partial least squares-discriminant analysis indicated that male GDM offspring present lower kidney, body, and brown adipose tissue weights; lower IL-1α levels, and higher concentrations of GM-CSF and IL-10 compared with their FFD counterparts. The model failed to select discriminative variables in females. In conclusion, in mice, maternal GDM in the absence of obesity adversely affects the early growth of juvenile male offspring.We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and parameters of the cardiometabolic status (glycemia, liver lipid content; body, organ, and fat weight) were determined. Two-factor analysis of variance indicated that the male offspring of GDM dams manifest postnatal growth retardation and lower relative kidney weight. Regardless of sex, GDM offspring manifest the lowest IL-1α levels, and other inflammatory markers showed mild and inconsistent alterations. Offspring of dams consuming the FFD displayed higher liver triacylglycerols content. The three groups of offspring showed no significant differences in glycemia and extracellular DNA. Partial least squares-discriminant analysis indicated that male GDM offspring present lower kidney, body, and brown adipose tissue weights; lower IL-1α levels, and higher concentrations of GM-CSF and IL-10 compared with their FFD counterparts. The model failed to select discriminative variables in females. In conclusion, in mice, maternal GDM in the absence of obesity adversely affects the early growth of juvenile male offspring.
Abstract We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and parameters of the cardiometabolic status (glycemia, liver lipid content; body, organ, and fat weight) were determined. Two-factor analysis of variance indicated that the male offspring of GDM dams manifest postnatal growth retardation and lower relative kidney weight. Regardless of sex, GDM offspring manifest the lowest IL-1α levels, and other inflammatory markers showed mild and inconsistent alterations. Offspring of dams consuming the FFD displayed higher liver triacylglycerols content. The three groups of offspring showed no significant differences in glycemia and extracellular DNA. Partial least squares-discriminant analysis indicated that male GDM offspring present lower kidney, body, and brown adipose tissue weights; lower IL-1α levels, and higher concentrations of GM-CSF and IL-10 compared with their FFD counterparts. The model failed to select discriminative variables in females. In conclusion, in mice, maternal GDM in the absence of obesity adversely affects the early growth of juvenile male offspring.
ArticleNumber 1700
Author Uličná, Oľga
Šebeková, Katarína
Mihalovičová, Lucia
Rausová, Zuzana
Gurecká, Radana
Janko, Jakub
Pastorek, Michal
Kunšteková, Veronika
Celec, Peter
Miláček, Dávid
Konečná, Barbora
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Cites_doi 10.1002/oby.21165
10.1038/s41374-019-0344-4
10.1093/biolre/ioz009
10.1097/md.0000000000022152
10.1136/bmjdrc-2019-000650
10.1293/tox.2017-0006
10.3390/ijms22158087
10.3390/ijms20122890
10.1038/s41598-021-97487-x
10.1016/S0022-2275(20)40355-4
10.1152/ajpendo.00425.2013
10.1111/sji.12651
10.1080/07315724.2004.10719428
10.3390/ijms21249408
10.1038/ki.1996.186
10.3390/biomedicines10020294
10.1016/0272-6386(95)90161-2
10.1093/clinchem/39.3.448
10.1016/j.diabres.2021.109050
10.3390/biom10071036
10.2105/ajph.2009.172890
10.1126/sciadv.1501332
10.1038/509282a
10.1007/s00125-018-4809-6
10.1186/s12974-017-0859-9
10.1007/s40618-016-0607-5
10.1073/pnas.91.20.9559
10.3390/ijms21218062
10.1111/j.1741-4520.1989.tb00741.x
10.1113/jp270429
10.1007/s11892-019-1267-6
10.1055/a-1787-3838
10.2147/dmso.S270935
10.1080/13813455.2021.1991957
10.3390/nu14030594
10.1007/s13300-022-01210-6
10.1530/jme-18-0274
10.5114/aoms.2016.58928
10.1016/S0021-9258(19)50907-3
10.1155/2012/254976
10.1038/s41598-019-52583-x
10.1155/edr.2003.107
10.1016/j.diabet.2018.06.004
10.1007/s11892-015-0699-x
10.1016/j.metabol.2004.11.003
10.3390/nu12010163
10.1590/s0102-865020180040000002
10.1126/science.1092385
10.1080/15384047.2019.1598759
10.2337/dc14-2159
10.1038/oby.2012.138
10.1016/0026-0495(88)90192-8
10.1016/j.anndiagpath.2008.06.002
10.1152/physiolgenomics.00029.2021
10.1210/jc.2003-032097
10.1016/j.mce.2021.111413
10.1159/000491066
10.1038/nri1391
10.1056/NEJMoa0707943
10.1038/s42255-022-00570-4
10.1371/journal.pone.0119784
10.1681/asn.2007080864
10.1016/j.jnutbio.2014.06.011
10.3389/fendo.2018.00542
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References Padmanabhan, Al-Zuhair (CR25) 1989; 29
Valencak, Hoffman (CR50) 2021; 536
Zhu, Zhang (CR4) 2016; 16
Zhou, Pan (CR60) 2015; 26
Ellulu, Patimah, Khazaai, Rahmat, Abed (CR61) 2017; 13
Song (CR36) 2012; 2012
Talton, Bates, Salazar, Ji, Schulz (CR33) 2019; 100
He (CR23) 2020; 13
López-Soldado, Herrera (CR35) 2003; 4
Li (CR46) 2020; 99
Nishimoto, Fukuda, Higashikuni, Tanaka, Hirata (CR19) 2016; 2
Mackenzie, Brenner (CR47) 1995; 26
Gutaj (CR9) 2020; 21
Bianco, Josefson (CR41) 2019; 19
Matuszewska (CR59) 2021; 11
Witko-Sarsat (CR55) 1996; 49
Lu (CR30) 2021; 1
Brenner, Mackenzie (CR48) 1997; 63
Weiskirchen, Weiper, Tolba, Weiskirchen (CR44) 2020; 12
Seely (CR49) 2017; 30
Nguyen-Ngo, Jayabalan, Salomon, Lappas (CR56) 2019; 63
Almog (CR58) 2019; 7
Clayton, Collins (CR38) 2014; 509
Kustanovich, Schwartz, Peretz, Grinshpun (CR53) 2019; 20
Pan, Jin, Wang, Hu, Dai (CR57) 2021; 13
Haghiac (CR18) 2012; 20
Brinkmann (CR54) 2004; 303
Imterat (CR22) 2022
Chang (CR32) 2019; 9
Turhan (CR26) 2018; 33
Grabuschnig (CR15) 2020; 21
Barker (CR6) 2004; 23
Zhou (CR51) 2020; 100
Moeckli (CR52) 2022; 10
Sandovici, Fernandez-Twinn, Hufnagel, Constância, Ozanne (CR42) 2022; 4
Gao, Ma, Liu (CR45) 2015; 10
Lieder (CR39) 2022; 14
Landon (CR8) 2014; 38
Pereira (CR28) 2015; 593
Nadano, Yasuda, Kishi (CR64) 1993; 39
Vuong (CR63) 2017; 14
Akira, Takeda (CR16) 2004; 4
Chiefari, Arcidiacono, Foti, Brunetti (CR1) 2017; 40
Konečná, Lauková, Vlková (CR13) 2018; 87
Goyal, Gupta, Tandon (CR2) 2022; 13
Konečná, Tóthová, Repiská (CR12) 2019; 20
Yang (CR62) 2018; 47
Metzger (CR7) 2008; 358
Oh, Gelardi, Cha (CR34) 1988; 37
Vokalova (CR14) 2018; 9
Abel, Levy, Brodie, Kendall (CR65) 1952; 195
Lappas, Permezel, Rice (CR10) 2004; 89
Pang, Mukonoweshuro, Wong (CR27) 1994; 91
Bartels (CR20) 2020; 46
Wang (CR3) 2022; 183
Pasek, Gannon (CR24) 2013; 305
Celec (CR21) 2021; 53
Tran (CR37) 2008; 19
Lowe (CR40) 2019; 62
Prayson, McMahon, Prayson (CR43) 2008; 12
Rosario, Kanai, Powell, Jansson (CR29) 2015; 23
Kim (CR5) 2010; 100
Olmos-Ortiz (CR11) 2021; 22
Lauková, Konečná, Janovičová, Vlková, Celec (CR17) 2020; 10
Buckley (CR31) 2005; 54
Jover (CR66) 1963; 4
B Moeckli (28903_CR52) 2022; 10
L Lauková (28903_CR17) 2020; 10
L Vokalova (28903_CR14) 2018; 9
Y Song (28903_CR36) 2012; 2012
WL Lowe Jr (28903_CR40) 2019; 62
V Brinkmann (28903_CR54) 2004; 303
A Olmos-Ortiz (28903_CR11) 2021; 22
P Celec (28903_CR21) 2021; 53
K Pang (28903_CR27) 1994; 91
I Sandovici (28903_CR42) 2022; 4
W Oh (28903_CR34) 1988; 37
JA Clayton (28903_CR38) 2014; 509
SY Kim (28903_CR5) 2010; 100
FJ Rosario (28903_CR29) 2015; 23
J Matuszewska (28903_CR59) 2021; 11
OO Talton (28903_CR33) 2019; 100
HS Mackenzie (28903_CR47) 1995; 26
D Zhou (28903_CR60) 2015; 26
Y Zhu (28903_CR4) 2016; 16
AJ Buckley (28903_CR31) 2005; 54
B Konečná (28903_CR13) 2018; 87
RC Pasek (28903_CR24) 2013; 305
MB Landon (28903_CR8) 2014; 38
S Grabuschnig (28903_CR15) 2020; 21
S Akira (28903_CR16) 2004; 4
YX Li (28903_CR46) 2020; 99
JC Seely (28903_CR49) 2017; 30
U Turhan (28903_CR26) 2018; 33
B Konečná (28903_CR12) 2019; 20
Y Zhou (28903_CR51) 2020; 100
M Gao (28903_CR45) 2015; 10
A Kustanovich (28903_CR53) 2019; 20
MS Bartels (28903_CR20) 2020; 46
P Gutaj (28903_CR9) 2020; 21
M Lappas (28903_CR10) 2004; 89
S Weiskirchen (28903_CR44) 2020; 12
S Nishimoto (28903_CR19) 2016; 2
M Imterat (28903_CR22) 2022
S Tran (28903_CR37) 2008; 19
A Jover (28903_CR66) 1963; 4
A Goyal (28903_CR2) 2022; 13
DJ Barker (28903_CR6) 2004; 23
TJ Pereira (28903_CR28) 2015; 593
C Nguyen-Ngo (28903_CR56) 2019; 63
E Chiefari (28903_CR1) 2017; 40
BM Brenner (28903_CR48) 1997; 63
R Padmanabhan (28903_CR25) 1989; 29
T Yang (28903_CR62) 2018; 47
E Chang (28903_CR32) 2019; 9
B Vuong (28903_CR63) 2017; 14
Y He (28903_CR23) 2020; 13
BE Metzger (28903_CR7) 2008; 358
ME Bianco (28903_CR41) 2019; 19
X Pan (28903_CR57) 2021; 13
T Almog (28903_CR58) 2019; 7
B Lieder (28903_CR39) 2022; 14
TG Valencak (28903_CR50) 2021; 536
B Prayson (28903_CR43) 2008; 12
H Wang (28903_CR3) 2022; 183
M Haghiac (28903_CR18) 2012; 20
D Nadano (28903_CR64) 1993; 39
MS Ellulu (28903_CR61) 2017; 13
V Witko-Sarsat (28903_CR55) 1996; 49
LL Abel (28903_CR65) 1952; 195
Y Lu (28903_CR30) 2021; 1
I López-Soldado (28903_CR35) 2003; 4
References_xml – volume: 23
  start-page: 1663
  year: 2015
  end-page: 1670
  ident: CR29
  article-title: Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth
  publication-title: Obesity
  doi: 10.1002/oby.21165
– volume: 100
  start-page: 553
  year: 2020
  end-page: 569
  ident: CR51
  article-title: Maternal diet intervention before pregnancy primes offspring lipid metabolism in liver
  publication-title: Lab. Invest.
  doi: 10.1038/s41374-019-0344-4
– volume: 100
  start-page: 1356
  year: 2019
  end-page: 1369
  ident: CR33
  article-title: Lean maternal hyperglycemia alters offspring lipid metabolism and susceptibility to diet-induced obesity in mice
  publication-title: Biol. Reprod.
  doi: 10.1093/biolre/ioz009
– volume: 99
  start-page: e22152
  year: 2020
  ident: CR46
  article-title: Gestational diabetes mellitus in women increased the risk of neonatal infection via inflammation and autophagy in the placenta
  publication-title: Medicine
  doi: 10.1097/md.0000000000022152
– volume: 7
  start-page: e000650
  year: 2019
  ident: CR58
  article-title: Interleukin-1α deficiency reduces adiposity, glucose intolerance and hepatic de-novo lipogenesis in diet-induced obese mice
  publication-title: BMJ Open Diabetes Res Care.
  doi: 10.1136/bmjdrc-2019-000650
– volume: 30
  start-page: 125
  year: 2017
  end-page: 133
  ident: CR49
  article-title: A brief review of kidney development, maturation, developmental abnormalities, and drug toxicity: Juvenile animal relevancy
  publication-title: J. Toxicol. Pathol.
  doi: 10.1293/tox.2017-0006
– volume: 22
  start-page: 8087
  year: 2021
  ident: CR11
  article-title: Immunoendocrine dysregulation during gestational diabetes mellitus: The central role of the placenta
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms22158087
– volume: 20
  start-page: 2890
  year: 2019
  ident: CR12
  article-title: Exosomes-associated DNA-new marker in pregnancy complications?
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms20122890
– volume: 11
  start-page: 18573
  year: 2021
  ident: CR59
  article-title: Mothers' cafeteria diet induced sex-specific changes in fat content, metabolic profiles, and inflammation outcomes in rat offspring
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-021-97487-x
– volume: 4
  start-page: 228
  year: 1963
  end-page: 230
  ident: CR66
  article-title: Technique for the determination of serum triglycerides
  publication-title: J. Lipid Res.
  doi: 10.1016/S0022-2275(20)40355-4
– volume: 305
  start-page: E1327
  year: 2013
  end-page: 1338
  ident: CR24
  article-title: Advancements and challenges in generating accurate animal models of gestational diabetes mellitus
  publication-title: Am. J. Physiol. Endocrinol. Metab.
  doi: 10.1152/ajpendo.00425.2013
– volume: 87
  start-page: e12651
  year: 2018
  ident: CR13
  article-title: Immune activation by nucleic acids: A role in pregnancy complications
  publication-title: Scand. J. Immunol.
  doi: 10.1111/sji.12651
– volume: 23
  start-page: 588s
  year: 2004
  end-page: 595s
  ident: CR6
  article-title: The developmental origins of adult disease
  publication-title: J. Am. Coll. Nutr.
  doi: 10.1080/07315724.2004.10719428
– volume: 21
  start-page: 9408
  year: 2020
  ident: CR9
  article-title: The role of the adipokines in the most common gestational complications
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms21249408
– volume: 49
  start-page: 1304
  year: 1996
  end-page: 1313
  ident: CR55
  article-title: Advanced oxidation protein products as a novel marker of oxidative stress in uremia
  publication-title: Kidney Int.
  doi: 10.1038/ki.1996.186
– volume: 10
  start-page: 294
  year: 2022
  ident: CR52
  article-title: Impact of maternal obesity on liver disease in the offspring: A comprehensive transcriptomic analysis and confirmation of results in a murine model
  publication-title: Biomedicines.
  doi: 10.3390/biomedicines10020294
– volume: 26
  start-page: 91
  year: 1995
  end-page: 98
  ident: CR47
  article-title: Fewer nephrons at birth: A missing link in the etiology of essential hypertension?
  publication-title: Am. J. Kidney Dis.
  doi: 10.1016/0272-6386(95)90161-2
– volume: 39
  start-page: 448
  year: 1993
  end-page: 452
  ident: CR64
  article-title: Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/39.3.448
– volume: 183
  start-page: 109050
  year: 2022
  ident: CR3
  article-title: IDF diabetes atlas: Estimation of global and regional gestational diabetes mellitus prevalence for 2021 by international association of diabetes in pregnancy study group's criteria
  publication-title: Diabetes Res. Clin. Pract.
  doi: 10.1016/j.diabres.2021.109050
– volume: 10
  start-page: 1036
  year: 2020
  ident: CR17
  article-title: Deoxyribonucleases and their applications in biomedicine
  publication-title: Biomolecules
  doi: 10.3390/biom10071036
– volume: 100
  start-page: 1047
  year: 2010
  end-page: 1052
  ident: CR5
  article-title: Percentage of gestational diabetes mellitus attributable to overweight and obesity
  publication-title: Am. J. Public Health.
  doi: 10.2105/ajph.2009.172890
– volume: 2
  start-page: e1501332
  year: 2016
  ident: CR19
  article-title: Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.1501332
– volume: 509
  start-page: 282
  year: 2014
  end-page: 283
  ident: CR38
  article-title: Policy: NIH to balance sex in cell and animal studies
  publication-title: Nature
  doi: 10.1038/509282a
– volume: 62
  start-page: 598
  year: 2019
  end-page: 610
  ident: CR40
  article-title: Maternal glucose levels during pregnancy and childhood adiposity in the hyperglycemia and adverse pregnancy outcome follow-up study
  publication-title: Diabetologia
  doi: 10.1007/s00125-018-4809-6
– volume: 14
  start-page: 80
  year: 2017
  ident: CR63
  article-title: Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring
  publication-title: J. Neuroinflamm.
  doi: 10.1186/s12974-017-0859-9
– volume: 40
  start-page: 899
  year: 2017
  end-page: 909
  ident: CR1
  article-title: Gestational diabetes mellitus: An updated overview
  publication-title: J. Endocrinol. Invest.
  doi: 10.1007/s40618-016-0607-5
– volume: 91
  start-page: 9559
  year: 1994
  end-page: 9563
  ident: CR27
  article-title: Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas
  publication-title: Proc. Natl. Acad. Sci. USA.
  doi: 10.1073/pnas.91.20.9559
– volume: 63
  start-page: S124
  year: 1997
  end-page: 127
  ident: CR48
  article-title: Nephron mass as a risk factor for progression of renal disease
  publication-title: Kidney Int. Suppl.
– volume: 21
  start-page: 8062
  year: 2020
  ident: CR15
  article-title: Putative origins of cell-free DNA in humans: A review of active and passive nucleic acid release mechanisms
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms21218062
– volume: 29
  start-page: 151
  year: 1989
  end-page: 163
  ident: CR25
  article-title: Effect of streptozotocin induced maternal diabetes on fetal skeletal development in the rat
  publication-title: Congenit. Anomal.
  doi: 10.1111/j.1741-4520.1989.tb00741.x
– volume: 593
  start-page: 3181
  year: 2015
  end-page: 3197
  ident: CR28
  article-title: Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome
  publication-title: J. Physiol.
  doi: 10.1113/jp270429
– volume: 19
  start-page: 143
  year: 2019
  ident: CR41
  article-title: Hyperglycemia during pregnancy and long-term offspring outcomes
  publication-title: Curr. Diabetes Rep.
  doi: 10.1007/s11892-019-1267-6
– year: 2022
  ident: CR22
  article-title: Cord blood cell-free DNA concentration: A novel marker for neonatal wellbeing
  publication-title: Am. J. Perinatol.
  doi: 10.1055/a-1787-3838
– volume: 13
  start-page: 4235
  year: 2020
  end-page: 4247
  ident: CR23
  article-title: Research progress on the experimental animal model of gestational diabetes mellitus
  publication-title: Diabetes Metab. Syndr. Obes.
  doi: 10.2147/dmso.S270935
– volume: 1
  start-page: 1
  year: 2021
  end-page: 13
  ident: CR30
  article-title: Progenies of gestational diabetes mellitus exhibit sex disparity in metabolism after respective therapies of insulin, glibenclamide, and metformin in dams during pregnancy
  publication-title: Arch. Physiol. Biochem.
  doi: 10.1080/13813455.2021.1991957
– volume: 14
  start-page: 594
  year: 2022
  ident: CR39
  article-title: Long-Term consumption of a sugar-sweetened soft drink in combination with a western-type diet is associated with morphological and molecular changes of taste markers independent of body weight development in mice
  publication-title: Nutrients
  doi: 10.3390/nu14030594
– volume: 13
  start-page: 589
  year: 2022
  end-page: 600
  ident: CR2
  article-title: Overt diabetes in pregnancy
  publication-title: Diabetes Ther.
  doi: 10.1007/s13300-022-01210-6
– volume: 63
  start-page: R51
  year: 2019
  end-page: r72
  ident: CR56
  article-title: Molecular pathways disrupted by gestational diabetes mellitus
  publication-title: J. Mol. Endocrinol.
  doi: 10.1530/jme-18-0274
– volume: 13
  start-page: 851
  year: 2017
  end-page: 863
  ident: CR61
  article-title: Obesity and inflammation: The linking mechanism and the complications
  publication-title: Arch. Med. Sci.
  doi: 10.5114/aoms.2016.58928
– volume: 195
  start-page: 357
  year: 1952
  end-page: 366
  ident: CR65
  article-title: A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(19)50907-3
– volume: 2012
  start-page: 254976
  year: 2012
  ident: CR36
  article-title: Severe maternal hyperglycemia exacerbates the development of insulin resistance and fatty liver in the offspring on high fat diet
  publication-title: Exp. Diabetes Res.
  doi: 10.1155/2012/254976
– volume: 9
  start-page: 16027
  year: 2019
  ident: CR32
  article-title: Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-52583-x
– volume: 4
  start-page: 107
  year: 2003
  end-page: 118
  ident: CR35
  article-title: Different diabetogenic response to moderate doses of streptozotocin in pregnant rats, and its long-term consequences in the offspring
  publication-title: Exp. Diabesity Res.
  doi: 10.1155/edr.2003.107
– volume: 46
  start-page: 249
  year: 2020
  end-page: 252
  ident: CR20
  article-title: Increased circulating cell-free DNA in insulin resistance
  publication-title: Diabetes Metab.
  doi: 10.1016/j.diabet.2018.06.004
– volume: 16
  start-page: 7
  year: 2016
  ident: CR4
  article-title: Prevalence of gestational diabetes and risk of progression to type 2 diabetes: A global perspective
  publication-title: Curr. Diabetes Rep.
  doi: 10.1007/s11892-015-0699-x
– volume: 54
  start-page: 500
  year: 2005
  end-page: 507
  ident: CR31
  article-title: Altered body composition and metabolism in the male offspring of high fat-fed rats
  publication-title: Metabolism
  doi: 10.1016/j.metabol.2004.11.003
– volume: 12
  start-page: 163
  year: 2020
  ident: CR44
  article-title: All you can feed: Some comments on production of mouse diets used in biomedical research with special emphasis on non-alcoholic fatty liver disease research
  publication-title: Nutrients
  doi: 10.3390/nu12010163
– volume: 33
  start-page: 306
  year: 2018
  end-page: 313
  ident: CR26
  article-title: Investigation of the effect of gestational diabetes on fetal cardiac tissue in streptozotocin ınduced in rats
  publication-title: Acta Circ. Bras.
  doi: 10.1590/s0102-865020180040000002
– volume: 303
  start-page: 1532
  year: 2004
  end-page: 1535
  ident: CR54
  article-title: Neutrophil extracellular traps kill bacteria
  publication-title: Science
  doi: 10.1126/science.1092385
– volume: 20
  start-page: 1057
  year: 2019
  end-page: 1067
  ident: CR53
  article-title: Life and death of circulating cell-free DNA
  publication-title: Cancer Biol. Ther.
  doi: 10.1080/15384047.2019.1598759
– volume: 38
  start-page: 445
  year: 2014
  end-page: 452
  ident: CR8
  article-title: Mild gestational diabetes mellitus and long-term child health
  publication-title: Diabetes Care
  doi: 10.2337/dc14-2159
– volume: 20
  start-page: 2213
  year: 2012
  end-page: 2219
  ident: CR18
  article-title: Increased death of adipose cells, a path to release cell-free DNA into systemic circulation of obese women
  publication-title: Obesity
  doi: 10.1038/oby.2012.138
– volume: 37
  start-page: 1146
  year: 1988
  end-page: 1151
  ident: CR34
  article-title: Maternal hyperglycemia in pregnant rats: its effect on growth and carbohydrate metabolism in the offspring
  publication-title: Metabolism
  doi: 10.1016/0026-0495(88)90192-8
– volume: 12
  start-page: 406
  year: 2008
  end-page: 409
  ident: CR43
  article-title: Fast food hamburgers: What are we really eating?
  publication-title: Ann. Diagn. Pathol.
  doi: 10.1016/j.anndiagpath.2008.06.002
– volume: 53
  start-page: 309
  year: 2021
  end-page: 318
  ident: CR21
  article-title: Circulating extracellular DNA is in association with continuous metabolic syndrome score in healthy adolescents
  publication-title: Physiol. Genomics.
  doi: 10.1152/physiolgenomics.00029.2021
– volume: 89
  start-page: 5627
  year: 2004
  end-page: 5633
  ident: CR10
  article-title: Release of proinflammatory cytokines and 8-isoprostane from placenta, adipose tissue, and skeletal muscle from normal pregnant women and women with gestational diabetes mellitus
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jc.2003-032097
– volume: 536
  start-page: 111413
  year: 2021
  ident: CR50
  article-title: Sex differences in brown adipose tissue
  publication-title: Mol. Cell. Endocrinol.
  doi: 10.1016/j.mce.2021.111413
– volume: 13
  start-page: 4068
  year: 2021
  end-page: 4079
  ident: CR57
  article-title: Placenta inflammation is closely associated with gestational diabetes mellitus
  publication-title: Am. J. Transl. Res.
– volume: 47
  start-page: 1862
  year: 2018
  end-page: 1870
  ident: CR62
  article-title: Maternal high-fat diet promotes the development and progression of prostate cancer in transgenic adenocarcinoma mouse prostate offspring
  publication-title: Cell Physiol. Biochem.
  doi: 10.1159/000491066
– volume: 4
  start-page: 499
  year: 2004
  end-page: 511
  ident: CR16
  article-title: Toll-like receptor signalling
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri1391
– volume: 358
  start-page: 1991
  year: 2008
  end-page: 2002
  ident: CR7
  article-title: Hyperglycemia and adverse pregnancy outcomes
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa0707943
– volume: 4
  start-page: 507
  year: 2022
  end-page: 523
  ident: CR42
  article-title: Sex differences in the intergenerational inheritance of metabolic traits
  publication-title: Nat. Metab.
  doi: 10.1038/s42255-022-00570-4
– volume: 10
  start-page: e0119784
  year: 2015
  ident: CR45
  article-title: High-fat diet-induced adiposity, adipose inflammation, hepatic steatosis and hyperinsulinemia in outbred CD-1 mice
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0119784
– volume: 19
  start-page: 943
  year: 2008
  end-page: 952
  ident: CR37
  article-title: Maternal diabetes modulates renal morphogenesis in offspring
  publication-title: J. Am. Soc. Nephrol.
  doi: 10.1681/asn.2007080864
– volume: 26
  start-page: 1
  year: 2015
  end-page: 8
  ident: CR60
  article-title: Pathophysiological basis for compromised health beyond generations: Role of maternal high-fat diet and low-grade chronic inflammation
  publication-title: J. Nutr. Biochem.
  doi: 10.1016/j.jnutbio.2014.06.011
– volume: 9
  start-page: 542
  year: 2018
  ident: CR14
  article-title: Excessive neutrophil activity in gestational diabetes mellitus: Could it contribute to the development of preeclampsia?
  publication-title: Front. Endocrinol.
  doi: 10.3389/fendo.2018.00542
– volume: 62
  start-page: 598
  year: 2019
  ident: 28903_CR40
  publication-title: Diabetologia
  doi: 10.1007/s00125-018-4809-6
– volume: 19
  start-page: 943
  year: 2008
  ident: 28903_CR37
  publication-title: J. Am. Soc. Nephrol.
  doi: 10.1681/asn.2007080864
– volume: 13
  start-page: 589
  year: 2022
  ident: 28903_CR2
  publication-title: Diabetes Ther.
  doi: 10.1007/s13300-022-01210-6
– volume: 26
  start-page: 91
  year: 1995
  ident: 28903_CR47
  publication-title: Am. J. Kidney Dis.
  doi: 10.1016/0272-6386(95)90161-2
– volume: 305
  start-page: E1327
  year: 2013
  ident: 28903_CR24
  publication-title: Am. J. Physiol. Endocrinol. Metab.
  doi: 10.1152/ajpendo.00425.2013
– volume: 13
  start-page: 851
  year: 2017
  ident: 28903_CR61
  publication-title: Arch. Med. Sci.
  doi: 10.5114/aoms.2016.58928
– volume: 100
  start-page: 1047
  year: 2010
  ident: 28903_CR5
  publication-title: Am. J. Public Health.
  doi: 10.2105/ajph.2009.172890
– volume: 63
  start-page: R51
  year: 2019
  ident: 28903_CR56
  publication-title: J. Mol. Endocrinol.
  doi: 10.1530/jme-18-0274
– volume: 11
  start-page: 18573
  year: 2021
  ident: 28903_CR59
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-021-97487-x
– volume: 14
  start-page: 80
  year: 2017
  ident: 28903_CR63
  publication-title: J. Neuroinflamm.
  doi: 10.1186/s12974-017-0859-9
– volume: 37
  start-page: 1146
  year: 1988
  ident: 28903_CR34
  publication-title: Metabolism
  doi: 10.1016/0026-0495(88)90192-8
– volume: 63
  start-page: S124
  year: 1997
  ident: 28903_CR48
  publication-title: Kidney Int. Suppl.
– volume: 100
  start-page: 553
  year: 2020
  ident: 28903_CR51
  publication-title: Lab. Invest.
  doi: 10.1038/s41374-019-0344-4
– volume: 20
  start-page: 2890
  year: 2019
  ident: 28903_CR12
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms20122890
– volume: 29
  start-page: 151
  year: 1989
  ident: 28903_CR25
  publication-title: Congenit. Anomal.
  doi: 10.1111/j.1741-4520.1989.tb00741.x
– volume: 46
  start-page: 249
  year: 2020
  ident: 28903_CR20
  publication-title: Diabetes Metab.
  doi: 10.1016/j.diabet.2018.06.004
– volume: 19
  start-page: 143
  year: 2019
  ident: 28903_CR41
  publication-title: Curr. Diabetes Rep.
  doi: 10.1007/s11892-019-1267-6
– volume: 54
  start-page: 500
  year: 2005
  ident: 28903_CR31
  publication-title: Metabolism
  doi: 10.1016/j.metabol.2004.11.003
– volume: 33
  start-page: 306
  year: 2018
  ident: 28903_CR26
  publication-title: Acta Circ. Bras.
  doi: 10.1590/s0102-865020180040000002
– volume: 358
  start-page: 1991
  year: 2008
  ident: 28903_CR7
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa0707943
– volume: 38
  start-page: 445
  year: 2014
  ident: 28903_CR8
  publication-title: Diabetes Care
  doi: 10.2337/dc14-2159
– volume: 10
  start-page: e0119784
  year: 2015
  ident: 28903_CR45
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0119784
– year: 2022
  ident: 28903_CR22
  publication-title: Am. J. Perinatol.
  doi: 10.1055/a-1787-3838
– volume: 20
  start-page: 1057
  year: 2019
  ident: 28903_CR53
  publication-title: Cancer Biol. Ther.
  doi: 10.1080/15384047.2019.1598759
– volume: 89
  start-page: 5627
  year: 2004
  ident: 28903_CR10
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jc.2003-032097
– volume: 100
  start-page: 1356
  year: 2019
  ident: 28903_CR33
  publication-title: Biol. Reprod.
  doi: 10.1093/biolre/ioz009
– volume: 23
  start-page: 588s
  year: 2004
  ident: 28903_CR6
  publication-title: J. Am. Coll. Nutr.
  doi: 10.1080/07315724.2004.10719428
– volume: 99
  start-page: e22152
  year: 2020
  ident: 28903_CR46
  publication-title: Medicine
  doi: 10.1097/md.0000000000022152
– volume: 20
  start-page: 2213
  year: 2012
  ident: 28903_CR18
  publication-title: Obesity
  doi: 10.1038/oby.2012.138
– volume: 21
  start-page: 9408
  year: 2020
  ident: 28903_CR9
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms21249408
– volume: 195
  start-page: 357
  year: 1952
  ident: 28903_CR65
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(19)50907-3
– volume: 9
  start-page: 542
  year: 2018
  ident: 28903_CR14
  publication-title: Front. Endocrinol.
  doi: 10.3389/fendo.2018.00542
– volume: 4
  start-page: 499
  year: 2004
  ident: 28903_CR16
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri1391
– volume: 9
  start-page: 16027
  year: 2019
  ident: 28903_CR32
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-52583-x
– volume: 40
  start-page: 899
  year: 2017
  ident: 28903_CR1
  publication-title: J. Endocrinol. Invest.
  doi: 10.1007/s40618-016-0607-5
– volume: 53
  start-page: 309
  year: 2021
  ident: 28903_CR21
  publication-title: Physiol. Genomics.
  doi: 10.1152/physiolgenomics.00029.2021
– volume: 536
  start-page: 111413
  year: 2021
  ident: 28903_CR50
  publication-title: Mol. Cell. Endocrinol.
  doi: 10.1016/j.mce.2021.111413
– volume: 13
  start-page: 4235
  year: 2020
  ident: 28903_CR23
  publication-title: Diabetes Metab. Syndr. Obes.
  doi: 10.2147/dmso.S270935
– volume: 509
  start-page: 282
  year: 2014
  ident: 28903_CR38
  publication-title: Nature
  doi: 10.1038/509282a
– volume: 13
  start-page: 4068
  year: 2021
  ident: 28903_CR57
  publication-title: Am. J. Transl. Res.
– volume: 14
  start-page: 594
  year: 2022
  ident: 28903_CR39
  publication-title: Nutrients
  doi: 10.3390/nu14030594
– volume: 12
  start-page: 163
  year: 2020
  ident: 28903_CR44
  publication-title: Nutrients
  doi: 10.3390/nu12010163
– volume: 87
  start-page: e12651
  year: 2018
  ident: 28903_CR13
  publication-title: Scand. J. Immunol.
  doi: 10.1111/sji.12651
– volume: 23
  start-page: 1663
  year: 2015
  ident: 28903_CR29
  publication-title: Obesity
  doi: 10.1002/oby.21165
– volume: 12
  start-page: 406
  year: 2008
  ident: 28903_CR43
  publication-title: Ann. Diagn. Pathol.
  doi: 10.1016/j.anndiagpath.2008.06.002
– volume: 183
  start-page: 109050
  year: 2022
  ident: 28903_CR3
  publication-title: Diabetes Res. Clin. Pract.
  doi: 10.1016/j.diabres.2021.109050
– volume: 39
  start-page: 448
  year: 1993
  ident: 28903_CR64
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/39.3.448
– volume: 2012
  start-page: 254976
  year: 2012
  ident: 28903_CR36
  publication-title: Exp. Diabetes Res.
  doi: 10.1155/2012/254976
– volume: 303
  start-page: 1532
  year: 2004
  ident: 28903_CR54
  publication-title: Science
  doi: 10.1126/science.1092385
– volume: 4
  start-page: 228
  year: 1963
  ident: 28903_CR66
  publication-title: J. Lipid Res.
  doi: 10.1016/S0022-2275(20)40355-4
– volume: 21
  start-page: 8062
  year: 2020
  ident: 28903_CR15
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms21218062
– volume: 49
  start-page: 1304
  year: 1996
  ident: 28903_CR55
  publication-title: Kidney Int.
  doi: 10.1038/ki.1996.186
– volume: 26
  start-page: 1
  year: 2015
  ident: 28903_CR60
  publication-title: J. Nutr. Biochem.
  doi: 10.1016/j.jnutbio.2014.06.011
– volume: 4
  start-page: 107
  year: 2003
  ident: 28903_CR35
  publication-title: Exp. Diabesity Res.
  doi: 10.1155/edr.2003.107
– volume: 593
  start-page: 3181
  year: 2015
  ident: 28903_CR28
  publication-title: J. Physiol.
  doi: 10.1113/jp270429
– volume: 2
  start-page: e1501332
  year: 2016
  ident: 28903_CR19
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.1501332
– volume: 4
  start-page: 507
  year: 2022
  ident: 28903_CR42
  publication-title: Nat. Metab.
  doi: 10.1038/s42255-022-00570-4
– volume: 30
  start-page: 125
  year: 2017
  ident: 28903_CR49
  publication-title: J. Toxicol. Pathol.
  doi: 10.1293/tox.2017-0006
– volume: 10
  start-page: 1036
  year: 2020
  ident: 28903_CR17
  publication-title: Biomolecules
  doi: 10.3390/biom10071036
– volume: 22
  start-page: 8087
  year: 2021
  ident: 28903_CR11
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms22158087
– volume: 7
  start-page: e000650
  year: 2019
  ident: 28903_CR58
  publication-title: BMJ Open Diabetes Res Care.
  doi: 10.1136/bmjdrc-2019-000650
– volume: 16
  start-page: 7
  year: 2016
  ident: 28903_CR4
  publication-title: Curr. Diabetes Rep.
  doi: 10.1007/s11892-015-0699-x
– volume: 1
  start-page: 1
  year: 2021
  ident: 28903_CR30
  publication-title: Arch. Physiol. Biochem.
  doi: 10.1080/13813455.2021.1991957
– volume: 47
  start-page: 1862
  year: 2018
  ident: 28903_CR62
  publication-title: Cell Physiol. Biochem.
  doi: 10.1159/000491066
– volume: 91
  start-page: 9559
  year: 1994
  ident: 28903_CR27
  publication-title: Proc. Natl. Acad. Sci. USA.
  doi: 10.1073/pnas.91.20.9559
– volume: 10
  start-page: 294
  year: 2022
  ident: 28903_CR52
  publication-title: Biomedicines.
  doi: 10.3390/biomedicines10020294
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Snippet We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD)...
Abstract We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food...
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SubjectTerms 631/136
631/337
631/443
692/4017
692/53
Adipose tissue
Adipose tissue (brown)
Animals
Blood glucose
Deoxyribonucleic acid
Diabetes mellitus
Diabetes, Gestational - metabolism
Diet
Discriminant analysis
DNA
Factor analysis
Fast food
Female
Gestational diabetes
Granulocyte-macrophage colony-stimulating factor
Growth rate
Humanities and Social Sciences
Humans
Inflammation
Interleukin 10
Kidneys
Liver
Liver - metabolism
Male
Mice
multidisciplinary
Nutrient deficiency
Obesity - complications
Offspring
Pregnancy
Prenatal Exposure Delayed Effects - metabolism
Science
Science (multidisciplinary)
Streptozocin
Variance analysis
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Title Severe gestational diabetes mellitus in lean dams is associated with low IL-1α levels and affects the growth of the juvenile mouse offspring
URI https://link.springer.com/article/10.1038/s41598-023-28903-7
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