Tricuspid valve disease: diagnosis, prognosis and management of a rapidly evolving field

• Published in: Nature reviews cardiology Vol. 16; no. 9; pp. 538 - 554
• Main Authors: Asmarats, Lluis, Taramasso, Maurizio, Rodés-Cabau, Josep
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.09.2019
• Subjects: Cardiac Valve Annuloplasty - adverse effects; Cardiac Valve Annuloplasty - instrumentation; Cardiac Valve Annuloplasty - methods; Cardiac Valve Annuloplasty - mortality; Catheters; Clinical medicine; Echocardiography, Three-Dimensional; Heart Valve Prosthesis Implantation - adverse effects; Heart Valve Prosthesis Implantation - methods; Heart Valve Prosthesis Implantation - mortality; Humans; Patient Selection; Practice Guidelines as Topic; Prognosis; Risk Assessment; Surgery; Tricuspid Valve Insufficiency - diagnosis; Tricuspid Valve Insufficiency - etiology; Tricuspid Valve Insufficiency - therapy; Tricuspid Valve Stenosis - diagnosis; Tricuspid Valve Stenosis - surgery
• ISSN: 1759-5002; 1759-5010
• DOI: 10.1038/s41569-019-0186-1

Tricuspid valve disease, and particularly tricuspid regurgitation, is a highly prevalent condition with a complex pathophysiology and long-term adverse consequences. Although historically neglected, tricuspid valve disease has gained increasing recognition, with important advances in the assessment and management of this disorder over the past 2 decades. Surgical treatment remains the standard of care, but it continues to have one of the the highest death rates among all cardiac valve-related procedures, and a broad range of patients still do not receive effective therapy for tricuspid valve disease in contemporary clinical practice. Therefore, several alternative, less-invasive technologies for treating patients with severe, native tricuspid valve disease at high surgical risk have been developed in the past decade, with promising early results. This Review summarizes key findings and highlights the latest developments in the diagnosis and management framework that are transforming clinical practice in the complex field of tricuspid valve disease.