A role for histone acetylation in regulating transcription elongation

Recently, we reported that a major function of histone acetylation at the yeast FLO1 gene was to regulate transcription elongation. Here, we discuss possible mechanisms by which histone acetylation might regulate RNA polymerase II processivity, and comment on the contribution to transcription of chr...

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Bibliographic Details
Published inTranscription Vol. 9; no. 4; pp. 225 - 232
Main Authors Church, Michael C., Fleming, Alastair B.
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 08.08.2018
Subjects
histone acetylation
Point-of-View
S. cerevisiae
SAGA
Swi-Snf
transcription elongation
Swi-Snf
transcription elongation
SAGA
histone acetylation
S. cerevisiae
Online AccessGet full text
ISSN2154-1264
2154-1272
2154-1272
DOI10.1080/21541264.2017.1394423

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Summary:Recently, we reported that a major function of histone acetylation at the yeast FLO1 gene was to regulate transcription elongation. Here, we discuss possible mechanisms by which histone acetylation might regulate RNA polymerase II processivity, and comment on the contribution to transcription of chromatin remodelling at gene coding regions and promoters.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
content type line 23
ISSN:2154-1264
2154-1272
2154-1272
DOI:10.1080/21541264.2017.1394423