How is electrical stimulation of the brain experienced, and how can we tell? Selected considerations on sensorimotor function and speech

• Published in: Cognitive neuropsychology Vol. 36; no. 3-4; pp. 103 - 116
• Main Authors: Mazurek, Kevin A., Schieber, Marc H.
• Format: Journal Article
• Language: English
• Published: England Routledge 19.05.2019
• Subjects: Brain - physiopathology; Cerebral cortex; Electric Stimulation - methods; electrical stimulation; Female; Humans; intracortical microstimulation; Male; perception; sensation; Somatosensory Cortex - physiology; Speech - physiology; electrical stimulation; Cerebral cortex; sensation; intracortical microstimulation; perception
• ISSN: 0264-3294; 1464-0627; 1464-0627
• DOI: 10.1080/02643294.2019.1609918

Electrical stimulation of the nervous system is a powerful tool for localizing and examining the function of numerous brain regions. Delivered to certain regions of the cerebral cortex, electrical stimulation can evoke a variety of first-order effects, including observable movements or an urge to move, or somatosensory, visual, or auditory percepts. In still other regions the subject may be oblivious to the stimulation. Often overlooked, however, is whether the subject is aware of the stimulation, and if so, how the stimulation is experienced by the subject. In this review of how electrical stimulation has been used to study selected aspects of sensorimotor and language function, we raise questions that future studies might address concerning the subjects' second-order experiences of intention and agency regarding evoked movements, of the naturalness of evoked sensory percepts, and of other qualia that might be evoked in the absence of an overt first-order experience.