Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma

• Published in: Clinical case reports Vol. 12; no. 3; pp. e8669 - n/a
• Main Authors: Karki, Diksha, Ngakhusi, Sajan
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.03.2024; John Wiley and Sons Inc; Wiley
• Subjects: Abdomen; adenocarcinoma; Cancer; Case Report; Case reports; Chemotherapy; Colon; Colonoscopy; Colorectal cancer; colorectal carcinoma; Consent; Cytoplasm; Family medical history; Females; Global Health; Healthcare Management; histopathology; Lymphatic system; Medical Education; Medical prognosis; Metastasis; Morphology; Mutation; Pathology and Laboratory Medicine; Proteins; sigmoid colon; Tumors; Asia; histopathology; adenocarcinoma; colorectal carcinoma; colonoscopy; sigmoid colon
• ISSN: 2050-0904; 2050-0904
• DOI: 10.1002/ccr3.8669

Key Clinical Message Serrated adenocarcinoma is a distinct subtype of colorectal carcinoma characterized by unique histological and molecular features. Here we present a case study of a 58‐year‐old female patient who presented with generalized weakness, abdominal discomfort, and per‐rectal bleeding. This case report highlights the importance of understanding the histopathological features of serrated adenocarcinoma for accurate diagnosis which has impact on further management.