Effect of a Novel Intracycle Motion Correction Algorithm on Dual-Energy Spectral Coronary CT Angiography: A Study with Pulsating Coronary Artery Phantom at High Heart Rates

• Published in: Korean journal of radiology Vol. 18; no. 6; pp. 881 - 887
• Main Authors: Xing, Yan, Zhao, Yuan, Guo, Ning, Pan, Cun-Xue, Azati, Gulina, Wang, Yan-Wei, Liu, Wen-Ya
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Radiology 01.11.2017; 대한영상의학회
• Subjects: Algorithms; Cardiovascular disease; Cardiovascular Imaging; Computed Tomography Angiography - instrumentation; Computed Tomography Angiography - methods; Confidence intervals; Coronary vessels; Coronary Vessels - diagnostic imaging; Coronary Vessels - physiology; Electrocardiography; Heart rate; Heart Rate - physiology; Humans; Iodine; Medical imaging; Radiation; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Vein & artery diseases; Work stations; 방사선과학; United States > US; Tomography, X-ray computed; Spectral imaging; Motion correction algorithm; Coronary arteries
• ISSN: 1229-6929; 2005-8330; 2005-8330
• DOI: 10.3348/kjr.2017.18.6.881

Using a pulsating coronary artery phantom at high heart rate settings, we investigated the efficacy of a motion correction algorithm (MCA) to improve the image quality in dual-energy spectral coronary CT angiography (CCTA). Coronary flow phantoms were scanned at heart rates of 60-100 beats/min at 10-beats/min increments, using dual-energy spectral CT mode. Virtual monochromatic images were reconstructed from 50 to 90 keV at 10-keV increments. Two blinded observers assessed image quality using a 4-point Likert Scale (1 = non-diagnostic, 4 = excellent) and the fraction of interpretable segments using MCA versus conventional algorithm (CA). Comparison of variables was performed with the Wilcoxon rank sum test and McNemar test. At heart rates of 70, 80, 90, and 100 beats/min, images with MCA were rated as higher image scores compared to those with CA on monochromatic levels of 50, 60, and 70 keV (each < 0.05). Meanwhile, at a heart rate of 90 beats/min, image interpretability was improved by MCA at a monochromatic level of 60 keV ( < 0.05) and 70 keV ( < 0.05). At a heart rate of 100 beats/min, image interpretability was improved by MCA at monochromatic levels of 50 keV (from 69.4% to 86.1%, < 0.05), 60 keV (from 55.6% to 83.3%, < 0.05) and 70 keV (from 33.3% to 69.3%, < 0.05). Low-keV monochromatic images combined with MCA improves image quality and image interpretability in CCTAs at high heart rates.