Digesting cytotoxic stressors – an unconventional mechanism to induce autophagy

Autophagy is an essential and fundamental pathway that clears unwanted or damaged material from the cell. Initiation of autophagy was previously shown to be dependent on the Ulk1/2 kinase complex. In this issue of The FEBS Journal, Braden and Neufeld investigated the Ulk3 homolog in Drosophila, and...

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Published inThe FEBS journal Vol. 283; no. 21; pp. 3886 - 3888
Main Authors Langlois, Christine R., Wollert, Thomas
Format Journal Article
LanguageEnglish
Published England Blackwell Publishing Ltd 01.11.2016
Subjects
Autophagy
Cytotoxicity
Drosophila
Kinases
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ISSN1742-464X
1742-4658
1742-4658
DOI10.1111/febs.13919

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Summary:Autophagy is an essential and fundamental pathway that clears unwanted or damaged material from the cell. Initiation of autophagy was previously shown to be dependent on the Ulk1/2 kinase complex. In this issue of The FEBS Journal, Braden and Neufeld investigated the Ulk3 homolog in Drosophila, and proposed a novel, Ulk1/2 independent pathway for autophagy initiation.
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ISSN:1742-464X
1742-4658
1742-4658
DOI:10.1111/febs.13919