The NGF Point-Injection for Treatment of the Sound-Perceiving Nerve Deafness and Tinnitus in 68 Cases

• Published in: Journal of traditional Chinese medicine Vol. 29; no. 1; pp. 39 - 42
• Main Author: 周枫 吴萍 王黎 王海涛 章少彬 林薏 钟慧 陈燕华
• Format: Journal Article
• Language: English
• Published: China 01.03.2009
• Subjects: Acupuncture Points; Adenosine Triphosphate - administration & dosage; Administration, Oral; Adolescent; Adult; Deafness - drug therapy; Drugs, Chinese Herbal - administration & dosage; Female; Humans; Injections; Male; Middle Aged; Nerve Growth Factor - administration & dosage; Tinnitus - drug therapy; Young Adult; 三磷酸腺苷; 感知; 治疗效果; 神经性耳聋; 神经生长因子; 穴位注射治疗; 维生素B12; 耳鸣
• ISSN: 0255-2922
• DOI: 10.1016/S0254-6272(09)60029-7

Objective： To observe the therapeutic effects of the point-injection with nerve growth factor （NGF） for the sound-perceiving nerve deafness and tinnitus. Methods： The 140 cases in this series were randomly divided into a treatment group of 68 cases treated by NGF injection at the points of Yifeng （TE 17） and Wangu （GB 12）, and a control group of 72 cases orally taking Xibiling （西比灵） and adenosine triphosphate （ATP） and intramuscular injection with VB1 and VB12. Results： The total effective rate was 78.6% in the treatment group and 31.8% in the control group, with significant difference between the two groups （P〈0.05）. Conclusion： For treating nervous deafness and tinnitus, NGF point-injection may show good therapeutic effects, but inversely proportional to the illness course, age and the extent of hypoacusis.