Biologically Enhanced Healing of the Rotator Cuff

• Published in: Orthopedics (Thorofare, N.J.) Vol. 35; no. 6; pp. 498 - 504
• Main Authors: Gordon, Nicole M., Maxson, Scott, Hoffman, James K.
• Format: Journal Article
• Language: English
• Published: Thorofare, NJ Slack 01.06.2012; SLACK INCORPORATED
• Subjects: Biological and medical sciences; Biological Products - therapeutic use; Case reports; Combined Modality Therapy; Diseases of the osteoarticular system; Humans; Male; Medical sciences; Mesenchymal Stem Cell Transplantation; Middle Aged; Platelet-Rich Plasma; Recovery of Function; Rotator Cuff Injuries; Skin Transplantation; Tendon Injuries - therapy; Treatment Outcome; Wound Healing; Cicatrization; Orthopedics; Rotator cuff
• ISSN: 0147-7447; 1938-2367; 1938-2367
• DOI: 10.3928/01477447-20120525-06

Failure of rotator cuff repair is a well-documented problem. Successful repair is impeded by muscle atrophy, fat infiltration, devascularization, and scar tissue formation throughout the fibrocartilagenous transition zone. This case study exemplifies a technique to biologically augment rotator cuff healing. Clinically, pain and function improved. Postoperative magnetic resonance imaging evaluation confirmed construct integrity. Biological enhancement of the healing process and physiologically based alterations in rehabilitation protocols can successfully treat complicated rotator cuff tears. Prospective studies with larger sample sizes and continued follow-up are necessary to assess the definitive efficacy of this treatment modality.