PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0

• Published in: European journal of nuclear medicine and molecular imaging Vol. 50; no. 5; pp. 1466 - 1486
• Main Authors: Fendler, Wolfgang P., Eiber, Matthias, Beheshti, Mohsen, Bomanji, Jamshed, Calais, Jeremie, Ceci, Francesco, Cho, Steve Y., Fanti, Stefano, Giesel, Frederik L., Goffin, Karolien, Haberkorn, Uwe, Jacene, Heather, Koo, Phillip J., Kopka, Klaus, Krause, Bernd J., Lindenberg, Liza, Marcus, Charles, Mottaghy, Felix M., Oprea-Lager, Daniela E., Osborne, Joseph R., Piert, Morand, Rowe, Steven P., Schöder, Heiko, Wan, Simon, Wester, Hans-Jürgen, Hope, Thomas A., Herrmann, Ken
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2023
• Subjects: Cardiology; Edetic Acid; Gallium Radioisotopes; Guidelines; Humans; Imaging; Male; Medicine; Medicine & Public Health; Nuclear Medicine; Oligopeptides; Oncology; Oncology – Genitourinary; Orthopedics; Positron Emission Tomography Computed Tomography - methods; Prostatic Neoplasms - diagnostic imaging; Radiology; Restaging; Guideline; PSMA; Staging; Prostate cancer; PET
• ISSN: 1619-7070; 1619-7089; 1619-7089
• DOI: 10.1007/s00259-022-06089-w

Here we aim to provide updated guidance and standards for the indication, acquisition, and interpretation of PSMA PET/CT for prostate cancer imaging. Procedures and characteristics are reported for a variety of available PSMA small radioligands. Different scenarios for the clinical use of PSMA-ligand PET/CT are discussed. This document provides clinicians and technicians with the best available evidence, to support the implementation of PSMA PET/CT imaging in research and routine practice.