A Case with Hematological Abnormality Characterized by the Absence of Peroxidase Activity in Blood Polymorphonuclear Leukocytes

A case with quite an unusual hematological abnormality characterized by the absence of peroxidase activity in the majority of polymorphonuclears and monocytes in blood was reported. This abnormality in the present patient was associated both with a megaloblastic anemia which was refractory to folic...

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Bibliographic Details
Published inThe Tohoku Journal of Experimental Medicine Vol. 87; no. 1; pp. 77 - 93
Main Authors Katsuyama, Nobuo, Satodate, Ryoichi, Higashi, Ototaka
Format Journal Article
LanguageEnglish
Published Japan Tohoku University Medical Press 01.01.1965
Subjects
Anemia, Macrocytic - complications
Child
Diagnosis, Differential
Female
Humans
Leukemia - diagnosis
Leukocytes - enzymology
Monocytes - enzymology
Peroxidases
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ISSN0040-8727
1349-3329
DOI10.1620/tjem.87.77

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Summary:A case with quite an unusual hematological abnormality characterized by the absence of peroxidase activity in the majority of polymorphonuclears and monocytes in blood was reported. This abnormality in the present patient was associated both with a megaloblastic anemia which was refractory to folic acid or vitamin B12 and also with a relatively mild proliferation of immature leuko-cytes in the bone marrow. The latter feature above all made us hesitate to diagnose the case as one kind of leukemic disease.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0040-8727
1349-3329
DOI:10.1620/tjem.87.77