Risk factors of hand eczema: A population‐based study among 900 subjects

• Published in: Contact dermatitis Vol. 87; no. 6; pp. 485 - 491
• Main Authors: Koskelo, Marjut, Sinikumpu, Suvi‐Päivikki, Jokelainen, Jari, Huilaja, Laura
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.12.2022; Wiley Subscription Services, Inc
• Subjects: alcohol consumption; Alcohol use; Atopic dermatitis; Dermatitis, Allergic Contact - complications; Dermatitis, Allergic Contact - etiology; Dermatitis, Atopic - complications; Dermatitis, Atopic - etiology; Eczema; Eczema - complications; Eczema - etiology; Environmental factors; Exercise; Female; hand eczema; Humans; Obesity; Obesity - complications; Original; Physical activity; Population studies; Population-based studies; risk factor; Risk Factors; Statistical analysis; Tobacco smoking; tobacco smoking; hand eczema; atopic dermatitis; alcohol consumption; risk factor; obesity; physical activity
• ISSN: 0105-1873; 1600-0536; 1600-0536
• DOI: 10.1111/cod.14205

Background Many risk factors such as atopic dermatitis (AD) have shown to associate with hand eczema (HE). However, studies concerning other atopic diseases, parental or longitudinal risk factors of HE are scarce. Objectives To examine the association between HE and atopic diseases, parental factors, environmental factors (keeping animals, exposure to moulds) and lifestyle factors (obesity, tobacco smoking, alcohol consumption and physical activity) at population level. Methods Subjects belonging to the Northern Finland Birth Cohort 1966 Study (NFBC1966) (n = 6830) answered a comprehensive health questionnaire. The data was completed with parental information. Results HE was reported in 900 (13.3%) individuals. All atopic diseases, parental allergy, female gender and obesity increased the risk of HE whereas physical activity decreased the risk of HE. A statistically significant association was not found between HE and tobacco smoking or alcohol consumption. Conclusions All atopic diseases, not only AD, seem to have influence on the presence of HE. In addition, parental and environmental factors associated with HE. In birth cohort setting (N = 6830), this study examined the prevalence and multiple risk factors of hand eczema (HE). HE was reported in 900 (13.3%) subjects. All atopic diseases, parental allergy, female gender and obesity increased the risk of HE whereas physical activity decreased the risk of HE.