Non-rigid deformation to include subject-specific detail in musculoskeletal models of CP children with proximal femoral deformity and its effect on muscle and contact forces during gait

• Published in: Computer methods in biomechanics and biomedical engineering Vol. 22; no. 4; pp. 376 - 385
• Main Authors: Wesseling, Mariska, Bosmans, Lode, Van Dijck, Christophe, Vander Sloten, Jos, Wirix-Speetjens, Roel, Jonkers, Ilse
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 12.03.2019; Taylor & Francis Ltd
• Subjects: Arm; Biomechanical Phenomena; Biomedical materials; Cerebral palsy; Cerebral Palsy - diagnostic imaging; Cerebral Palsy - physiopathology; Child; Children; Computer simulation; Contact force; Deformation effects; Female; Femur; Gait; Gait - physiology; Hip; Hip Joint - physiopathology; Humans; Magnetic Resonance Imaging; Male; Models, Biological; MRI; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - physiopathology; Muscles; musculoskeletal modelling; Musculoskeletal System - diagnostic imaging; Musculoskeletal System - physiopathology; NMR; non-rigid deformation; Nuclear magnetic resonance; Paralysis; Subject-specific; Surgical implants; Subject-specific; MRI; musculoskeletal modelling; non-rigid deformation
• ISSN: 1025-5842; 1476-8259; 1476-8259
• DOI: 10.1080/10255842.2018.1558216

To account for proximal femoral deformities in children with cerebral palsy (CP), subject-specific musculoskeletal models are needed. Non-rigid deformation (NRD) deforms generic onto personalized bone geometry and thereby transforms the muscle points. The goal of this study was to determine to what extent the models and simulation outcomes in CP patients differ when including subject-specific detail using NRD or Magnetic Resonance Imaging (MRI)-based models. The NRD models slightly overestimated hip contact forces compared to MRI models and differences in muscle point positions and moment arm lengths (MALs) remained, although differences were smaller than for the generic model.