Primary Glioblastoma of the Cerebellopontine Angle : Case Report and Review of the Literature

• Published in: Journal of Korean Neurosurgical Society Vol. 60; no. 3; pp. 380 - 384
• Main Authors: Lee, Ji-Hye, Kim, Jong Hyun, Kwon, Taek-Hyun
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Neurosurgical Society 01.05.2017; 대한신경외과학회
• Subjects: Case Report; 신경외과학; Glioblastoma multiforme; Extraaxial; Cerebellopontine angle
• ISSN: 2005-3711; 1598-7876
• DOI: 10.3340/jkns.2015.0303.006

Glioblastoma multiforme (GBM) is located most frequently in the cerebral hemispheres. Glioblastoma presenting as an extraaxial mass of cerebellopontine angle (CPA) is very rare in adults. We report a rare case of GBM arising in the CPA. The patient was a 71-year-old female, who complained of progressive gait disturbance and poor memory. Initial magnetic resonance imaging (MRI) revealed a 1.4×1.3 cm mass in the left CPA, with broad base to the petrous bone, showing homogenous enhancement. Follow-up MRI showed a rapid increase in size of mass (2.7×2.2 cm) with a necrotic portion. A stereotactic biopsy was done under the guidance of navigation system, and the histopathologic diagnosis was GBM, World Heath Organization grade IV. Further surgical resection was not performed considering her general condition, and the patient underwent concurrent chemotherapy with radiation therapy. Although rare, the possibility of glioblastoma should be included in the differential diagnosis of atypical CPA tumor.