Hemodynamic Changes on Color Doppler Flow Imaging and Intravenous Contrast-enhanced Ultrasound for Assessing Transplanted Liver and Early Diagnosis of Complications

• Published in: Journal of Huazhong University of Science and Technology. Medical sciences Vol. 28; no. 3; pp. 284 - 286
• Main Author: 黄道中 陈云超 李开艳 张青萍
• Format: Journal Article
• Language: English
• Published: Heidelberg Huazhong University of Science and Technology 01.06.2008; Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
• Subjects: Adult; Bile Ducts - pathology; Contrast Media - administration & dosage; Female; Hemodynamics; Hepatic Artery - pathology; Humans; Infusions, Intravenous - methods; Liver Transplantation - adverse effects; Liver Transplantation - diagnostic imaging; Liver Transplantation - methods; Male; Medicine; Medicine & Public Health; Middle Aged; Perfusion; Postoperative Complications; Ultrasonography - methods; Ultrasonography, Doppler - methods; 彩色多谱勒流动成像; 手术并发症; 肝移植; 血液动力学; postoperative complications; color Doppler flow imaging; liver transplantation; hemodynamics; intravenous contrast-enhanced ultrasound
• ISSN: 1672-0733; 1993-1352
• DOI: 10.1007/s11596-008-0312-5

The value of color Doppler flow imaging （CDFI） and intravenous contrast-enhanced ultrasound （CEUS） for assessing the transplanted liver and early diagnosing complications by examining hemodynamic changes was discussed. Seventy-five patients with orthotopic liver transplantation （OLT） underwent CDFI. The following parameters were measured： peak systolic velocity （PS）, resistance index （RI） and Doppler perfusion index （DPI） of the hepatic artery （HA）, time average velocity （TAV） of portal vein （PV） and velocity of hepatic vein （HV） in different stages postoperation, And 11 patients of them received CEUS. Thirty healthy subjects were enrolled as controls, The results showed that： （1） In 23 patients without obvious complications, TAV of PV within 15 days post-operation was significantly higher than in controls （P〈0.05）, PS and DPI of HA within 7 days postoperation were lower, but RI was higher than in controls （P〈0.05）; （2） When the hepatic artery thrombosis （HAT） occurred, PS and DPI of HA were obviously decreased, but TAV of PV significantly increased like a high saw-tooth wave; （3） While rejection occurred, both TAV of PV and PS of HA were decreased with the increase in RI of HA, and the triphasic wave of HV disappeared and displayed as saw-tooth wave; （4） The incidence of biliary complications in liver transplantation was increased when DPI was reduced; （5） Seven cases of hepatic carcinoma relapse after OLT demonstrated hyperecho in the arterial phase and hypoecho in the portal and later phase on CEUS; （6） In 2 cases of HA thrombus, there was no visualized enhancement in arterial phase of CEUS, but enhancement during the portal vein and parenchymal phase. It was concluded that the hemodynamic changes of PV, HA and HV in the transplanted liver are valuable for assessing the transplanted liver and early diagnosing complications on CDFI and CEUS.