Is Multi-Drug Resistant Tuberculosis More Prevalent in HIV-Infected Patients in Korea?

• Published in: Yonsei medical journal Vol. 57; no. 6; pp. 1508 - 1510
• Main Authors: Lee, Shinwon, Lee, Sun Hee, Mok, Jeong Ha, Lee, Su Jin, Kim, Kye-Hyung, Lee, Jeong Eun, Lee, Seung Geun, Chung, Joo Seop, Kwak, Ihm Soo
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 01.11.2016; 연세대학교의과대학
• Subjects: Adult; Antitubercular Agents - therapeutic use; Brief Communication; Case-Control Studies; Coinfection; Female; HIV Infections - complications; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV Infections - microbiology; Humans; Male; Middle Aged; Mycobacterium tuberculosis - drug effects; Mycobacterium tuberculosis - isolation & purification; Prevalence; Republic of Korea - epidemiology; Tuberculosis, Multidrug-Resistant - complications; Tuberculosis, Multidrug-Resistant - epidemiology; Tuberculosis, Multidrug-Resistant - microbiology; Tuberculosis, Pulmonary - diagnosis; Tuberculosis, Pulmonary - drug therapy; Tuberculosis, Pulmonary - epidemiology; 의학일반; MDR; HIV; intermediate TB burden; resistance
• ISSN: 0513-5796; 1976-2437
• DOI: 10.3349/ymj.2016.57.6.1508

The epidemiological synergy between human immunodeficiency virus (HIV) and tuberculosis (TB) is a major threat to public health. However, the association between HIV and multi-drug resistant tuberculosis (MDR-TB) is not clear. To explore the association between HIV and MDR-TB infection, a case-control study was performed in Korea. A total of 1606 culture-proven TB patients (45 HIV vs. 1561 non-HIV) from January 2006 to October 2014 were included in this analysis. MDR-TB rates were 11.1% and 8.2% in the HIV and non-HIV groups, respectively (p=0.42), thus indicating that MDR-TB was not significantly associated with HIV infection in Korea.