Chronic kidney disease in children

Chronic kidney disease (CKD) is a major health problem worldwide. Although relatively uncommon in children, it can be a devastating illness with many long-term consequences. CKD presents unique features in childhood and may be considered, at least in part, as a stand-alone nosologic entity. Moreover...

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Published inClinical kidney journal Vol. 9; no. 4; pp. 583 - 591
Main Authors Becherucci, Francesca, Roperto, Rosa Maria, Materassi, Marco, Romagnani, Paola
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.08.2016
Subjects
Chronic Kidney Disease
ESRD
paediatrics
chronic renal insufficiency
chronic renal failure
CKD
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ISSN2048-8505
2048-8513
DOI10.1093/ckj/sfw047

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Summary:Chronic kidney disease (CKD) is a major health problem worldwide. Although relatively uncommon in children, it can be a devastating illness with many long-term consequences. CKD presents unique features in childhood and may be considered, at least in part, as a stand-alone nosologic entity. Moreover, some typical features of paediatric CKD, such as the disease aetiology or cardiovascular complications, will not only influence the child's health, but also have long-term impact on the life of the adult that they will become. In this review we will focus on the unique issues of paediatric CKD, in terms of aetiology, clinical features and treatment. In addition, we will discuss factors related to CKD that start during childhood and require appropriate treatments in order to optimize health outcomes and transition to nephrologist management in adult life.
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F.B. and R.M.R. equally contributed to this work.
ISSN:2048-8505
2048-8513
DOI:10.1093/ckj/sfw047