A Case of More Abundant and Dysplastic Adenomas in the Interposed Colon than in the Native Colon

• Published in: Yonsei medical journal Vol. 48; no. 6; pp. 1075 - 1078
• Main Authors: Hwang, Hye Jin, Song, Kyung Ho, Youn, Young Hoon, Kwon, Ji Eun, Kim, Hoguen, Chung, Jae Bock, Lee, Yong Chan
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 31.12.2007; 연세대학교의과대학
• Subjects: Adenocarcinoma - pathology; Adenoma - etiology; Adenoma - pathology; Case Report; Colon - pathology; Colonic Neoplasms - etiology; Colonic Neoplasms - pathology; Disease Progression; Esophagoplasty - adverse effects; Esophagoplasty - methods; Female; Humans; Middle Aged; Postoperative Complications - etiology; Postoperative Complications - pathology; Time Factors; 의학일반
• ISSN: 0513-5796; 1976-2437; 1976-2437
• DOI: 10.3349/ymj.2007.48.6.1075

We report a 60-year-old woman with intramucosal adenocarcinoma arising in the interposed colon, 40 years after the esophageal reconstruction for lye induced esophageal stricture. Although synchronous adenomas were also found in the native colon where the graft was taken, the number of adenomas was greater in the interposed colon and more dysplastic, even progressed to adenocarcinoma, than that of the native colon. The microsatellite instability-testing performed in the intramucosal carcinoma from interposed colon showed absence of microsatellite instability. Changing of location and functional demand of colonic segment, and the exposure to different intraluminal contents might have facilitated the adenoma- carcinoma transformation in the interposed colon.