Two Cases of Antibody-Mediated Rejection Following Kidney Transplantation due to HLA-DQB1 Allele-Specific and DQ Alpha Protein-Specific HLA Antibodies

Dear Editor, The HLA-A, HLA-B, and HLA-DR loci have been used for transplant candidate matching. Recent studies using single antigen bead-based assays (SABAs) have revealed that HLA-DQ donor-specific HLA antibodies (DSHAs) are associated with inferior allograft outcomes [1, 2]. Therefore, donor HLA-...

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Bibliographic Details
Published inAnnals of laboratory medicine Vol. 37; no. 3; pp. 290 - 292
Main Authors Song, Seung Hwan, Park, Borae G., Kim, Beom Seok, Kim, Yu Seun, Kim, Hyon-Suk
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Society for Laboratory Medicine 01.05.2017
대한진단검사의학회
Subjects
Alleles
Female
Graft Rejection - diagnosis
Graft Rejection - etiology
Graft Rejection - immunology
Histocompatibility Testing
HLA-DQ alpha-Chains - immunology
HLA-DQ alpha-Chains - metabolism
HLA-DQ beta-Chains - immunology
HLA-DQ beta-Chains - metabolism
Humans
Isoantibodies - immunology
Kidney Transplantation - adverse effects
Letter to the Editor
Young Adult
병리학
Online AccessGet full text
ISSN2234-3806
2234-3814
2234-3814
DOI10.3343/alm.2017.37.3.290

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Summary:Dear Editor, The HLA-A, HLA-B, and HLA-DR loci have been used for transplant candidate matching. Recent studies using single antigen bead-based assays (SABAs) have revealed that HLA-DQ donor-specific HLA antibodies (DSHAs) are associated with inferior allograft outcomes [1, 2]. Therefore, donor HLA-DQ typing prior to transplantation is now thought to be highly important. KCI Citation Count: 1
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Correspondence-3
content type line 23
ObjectType-Report-1
ISSN:2234-3806
2234-3814
2234-3814
DOI:10.3343/alm.2017.37.3.290