Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report

Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only after two failed adequate antipsychotics trials. We report a cas...

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Published inClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology Vol. 11; no. 3; pp. 168 - 169
Main Authors Kim, Yeon-Jin, No, Seung-Ho, Lee, Sang-Yeol
Format Journal Article
LanguageEnglish
Published Korea (South) Korean College of Neuropsychopharmacology 01.12.2013
대한정신약물학회
Subjects
Case Report
정신과학
Antipsychotics
First-episode schizophrenia
Clozapine
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ISSN1738-1088
2093-4327
2093-4327
DOI10.9758/cpn.2013.11.3.168

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Summary:Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only after two failed adequate antipsychotics trials. We report a case of a successful early clozapine trial in the treatment of first-episode schizophrenia patient, considering poor treatment response and repeated self-injurious behavior. This case highlights the efficacy of an early clozapine trial as a second-line treatment for first-episode schizophrenia in contrast to switching or combination treatment strategy.
Bibliography:ObjectType-Article-1
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G704-002231.2013.11.3.003
ISSN:1738-1088
2093-4327
2093-4327
DOI:10.9758/cpn.2013.11.3.168