Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells
The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Al-pha-pinene, an...
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| Published in | Journal of exercise rehabilitation Vol. 15; no. 5; pp. 723 - 730 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korean Society of Exercise Rehabilitation
01.10.2019
한국운동재활학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2288-176X 2288-1778 |
| DOI | 10.12965/jer.1938442.221 |
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| Abstract | The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Al-pha-pinene, anti-inflammatory active compound of C. obtusa, was ana-lyzed by electrospray ionization-mass spectrometry, gas chromatogra-phy, and gas chromatography mass spectrometry from each part of ex-tracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw ma-terial for natural product industry. |
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| AbstractList | The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa, was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry.The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa, was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry. The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Al-pha-pinene, anti-inflammatory active compound of C. obtusa, was ana-lyzed by electrospray ionization-mass spectrometry, gas chromatogra-phy, and gas chromatography mass spectrometry from each part of ex-tracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw ma-terial for natural product industry. KCI Citation Count: 0 The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Al-pha-pinene, anti-inflammatory active compound of C. obtusa, was ana-lyzed by electrospray ionization-mass spectrometry, gas chromatogra-phy, and gas chromatography mass spectrometry from each part of ex-tracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw ma-terial for natural product industry. The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. ( C. obtusa ). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa , was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa . The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry. |
| Author | Kim, Yong-Min Kim, Ee-Hwa Kwak, Byeong Mun Kim, Hee-Tack |
| AuthorAffiliation | 3 Department of Korean Medical Ophthalmology & Otolaryngology & Dermatology, College of Korean Medicine, Semyung University, Jecheon, Korea 2 Department of Oriental Medical and Herbal Cosmetic Sciences, Semyung University, Jecheon, Korea 1 Department of Meridian & Acupoint, College of Korean Medicine, Semyung University, Jecheon, Korea |
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| Cites_doi | 10.1378/chest.112.6_Supplement.321S 10.1111/j.1365-2249.2006.03261.x 10.5213/inj.1734898.449 10.1080/000155599750011705 10.5213/inj.1836124.062 10.1016/j.jep.2010.05.054 10.1021/np400828x 10.1038/nrd1175 10.1142/S0192415X15500457 10.5213/inj.1732774.387 |
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| Copyright | Copyright © 2019 Korean Society of Exercise Rehabilitation. Copyright © 2019 Korean Society of Exercise Rehabilitation 2019 |
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| Keywords | Anti- inflammatory effect Supercritical fluid extraction Chamaecyparis obtusa Endl |
| Language | English |
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| Snippet | The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis... The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa... The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa... |
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| TableOfContents | Abstract
INTRODUCTION
MATERIALS AND METHODS
Supercritical fluid extraction
Fatty acid analysis
Electrospray ionization-mass spectrometry
Solid phase microextraction method
Nitric oxide assay
RESULTS
Supercritical fluid extraction
Fatty acid component
GC/MS analysis
Effects of extracts from C. obtusa and α-pinene on NO
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES |
| Title | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
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