Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases

• Published in: Brazilian journal of otorhinolaryngology Vol. 74; no. 6; pp. 941 - 944
• Main Authors: Freitas, Vinicius Antunes, Becker, Helena Maria Gonçalves, Guimarães, Roberto Eustáquio Santos, Franco, Letícia Paiva, Guimarães, Fernando Fernandes, Martins, Marcelo Figueredo, Crosara, Paulo Fernando Tormin
• Format: Journal Article
• Language: English
• Published: Brazil Elsevier Editora Ltda 01.11.2008; Elsevier
• Subjects: aerodigestive tract; Aged; Case Report; Humans; Male; Middle Aged; Mouth Diseases - diagnosis; Mouth Diseases - drug therapy; Mouth Diseases - etiology; Pemphigoid, Benign Mucous Membrane - complications; Pemphigoid, Benign Mucous Membrane - diagnosis; Pemphigoid, Benign Mucous Membrane - drug therapy; pemphygoid; scars; pemphygoid; scars; aerodigestive tract
• ISSN: 1808-8694; 1808-8686
• DOI: 10.1016/S1808-8694(15)30158-0

Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy.