Nitric Oxide–Containing Nanoparticles as an Antimicrobial Agent and Enhancer of Wound Healing

Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO,...

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Published inJournal of investigative dermatology Vol. 129; no. 10; pp. 2335 - 2337
Main Author Weller, Richard B.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2009
Elsevier Limited
Subjects
Animals
Anti-Infective Agents - pharmacology
Anti-Infective Agents - therapeutic use
Disease Models, Animal
Drug Delivery Systems
Mice
Nanoparticles - therapeutic use
Nitric Oxide - metabolism
Nitric Oxide - pharmacology
Nitric Oxide - therapeutic use
Staphylococcal Skin Infections - drug therapy
Staphylococcal Skin Infections - metabolism
Staphylococcus aureus
Treatment Outcome
Wound Healing - drug effects
Online AccessGet full text
ISSN0022-202X
1523-1747
1523-1747
DOI10.1038/jid.2009.149

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Abstract Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO, and they demonstrate its efficacy in treating infected wounds.
AbstractList Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO, and they demonstrate its efficacy in treating infected wounds.Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO, and they demonstrate its efficacy in treating infected wounds.
Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO, and they demonstrate its efficacy in treating infected wounds.
Author Weller, Richard B.
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/19749782$$D View this record in MEDLINE/PubMed
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Copyright 2009 The Society for Investigative Dermatology, Inc
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Snippet Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical...
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SubjectTerms Animals
Anti-Infective Agents - pharmacology
Anti-Infective Agents - therapeutic use
Disease Models, Animal
Drug Delivery Systems
Mice
Nanoparticles - therapeutic use
Nitric Oxide - metabolism
Nitric Oxide - pharmacology
Nitric Oxide - therapeutic use
Staphylococcal Skin Infections - drug therapy
Staphylococcal Skin Infections - metabolism
Staphylococcus aureus
Treatment Outcome
Wound Healing - drug effects
Title Nitric Oxide–Containing Nanoparticles as an Antimicrobial Agent and Enhancer of Wound Healing
URI https://dx.doi.org/10.1038/jid.2009.149
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