Nitric Oxide–Containing Nanoparticles as an Antimicrobial Agent and Enhancer of Wound Healing

Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO,...

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Bibliographic Details
Published inJournal of investigative dermatology Vol. 129; no. 10; pp. 2335 - 2337
Main Author Weller, Richard B.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2009
Elsevier Limited
Subjects
Animals
Anti-Infective Agents - pharmacology
Anti-Infective Agents - therapeutic use
Disease Models, Animal
Drug Delivery Systems
Mice
Nanoparticles - therapeutic use
Nitric Oxide - metabolism
Nitric Oxide - pharmacology
Nitric Oxide - therapeutic use
Staphylococcal Skin Infections - drug therapy
Staphylococcal Skin Infections - metabolism
Staphylococcus aureus
Treatment Outcome
Wound Healing - drug effects
Online AccessGet full text
ISSN0022-202X
1523-1747
1523-1747
DOI10.1038/jid.2009.149

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Summary:Nitric oxide (NO) is known to be involved in wound healing and to have antimicrobial actions. Developing a means of delivering a diatomic, gaseous free radical has been a technical challenge. Using a combination of techniques, Martinez and colleagues have developed an ingenious method of storing NO, and they demonstrate its efficacy in treating infected wounds.
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ISSN:0022-202X
1523-1747
1523-1747
DOI:10.1038/jid.2009.149