Assessing of the Italian version of the Memory Strategy Test (TMS) in people with Parkinson disease: a preliminary descriptive psychometric study

• Published in: Neurological sciences Vol. 44; no. 11; pp. 3895 - 3903
• Main Authors: Vaccaro, Maria Grazia, Pullano, Luca, Canino, Silvia, Pastore, Massimiliano, Sarica, Alessia, Quattrone, Andrea, Fernandes, Sara Margarida, Migliorini, Filippo, Maestu, Fernando, Quattrone, Aldo
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.11.2023; Springer Nature B.V
• Subjects: Cognitive ability; Executive function; Factor analysis; Medicine; Medicine & Public Health; Memory; Movement disorders; Neurodegenerative diseases; Neurology; Neuroradiology; Neurosciences; Neurosurgery; Original; Original Article; Parkinson's disease; Prediction models; Psychiatry; Quantitative psychology; Transcranial magnetic stimulation; Memory Strategies Test; Psychometric Properties; Parkinson’s disease; Neuropsychological Assessment; Executive Functions
• ISSN: 1590-1874; 1590-3478; 1590-3478
• DOI: 10.1007/s10072-023-06906-6

Background Previous literature has shown that executive functions (EF) are related to performance in memory (M) tasks. The Test of Memory strategies (TMS) is a psychometric test that examines EF and M simultaneously and it was recently validated on an Italian healthy cohort. The first aim of the study was to apply TMS, for the first time, on a sample of patients with Parkinson's disease (PD), who are characterized by mild cognitive impairment. The second aim is to investigate whether TMS scores can discriminate PD patients from healthy controls. Method Ninety-eight subjects were enrolled, including 68 patients with PD, and 30 Italian healthy controls (HC), who also underwent a memory evaluation through well-known tests . Results Confirmatory factor analysis (CFA) demonstrated that TMS of PD patients had a bi-dimensional structure as previously found in healthy cohort. In detail, The TMS-1 and TMS-2 lists require greater involvement of the EF factor, while TMS-3, TMS-4 and TMS-5 the M factor. Receiver operating characteristic (ROC) curves and precision-recall (PR) curves showed that the M subscale can distinguish between HC and PD, while EF had poor discrimination power. Conclusion The hypothesized prediction model of TMS test seems to have adequate ability to discriminate PD from HC especially for the M function.