Non-contrast MRI methods as a tool for the pre-operative assessment and surveillance of the arterio-venous fistula for haemodialysis

• Published in: Magma (New York, N.Y.) Vol. 31; no. 6; pp. 735 - 745
• Main Authors: MacDonald, Conor J., Gandy, Stephen, Avison, Eilidh C. M., Matthew, Shona, Ross, Rose, Houston, John G.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.12.2018
• Subjects: Adult; Arteriovenous Fistula - diagnostic imaging; Arteriovenous Shunt, Surgical; Biomedical Engineering and Bioengineering; Blood Flow Velocity; Brachial Artery - surgery; Computer Appl. in Life Sciences; Health Informatics; Humans; Image Processing, Computer-Assisted; Imaging; Imaging, Three-Dimensional; Kidney Failure, Chronic - diagnostic imaging; Kidney Failure, Chronic - surgery; Magnetic Resonance Imaging - methods; Medicine; Medicine & Public Health; Middle Aged; Pilot Projects; Preoperative Period; Radial Artery - surgery; Radiology; Renal Dialysis - adverse effects; Renal Dialysis - methods; Research Article; Solid State Physics; Ultrasonography; MRI; Ultrasound; Humans; Arterio-venous fistula
• ISSN: 0968-5243; 1352-8661; 1352-8661
• DOI: 10.1007/s10334-018-0700-1

Objective To compare non-contrast enhanced MRI with ultrasound (US) for measurement of arm blood vessel geometries and flow velocities in volunteers and patients with end-stage renal disease. Materials and methods Subjects were scanned using US (reference standard), and MRI 2D time-of-flight (ToF), 2D phase contrast (PC), and 3D multi-echo data image combination (MEDIC). Patients were also scanned after arteriovenous fistula (AVF) surgery. Results For mean vessel diameters (radial and brachial arteries; cephalic vein) MEDIC measurements were similar to US ( p  > 0.05). However, ToF underestimated the mean diameter of the cephalic vein relative to US ( p  < 0.05). For arterial velocity measurements, the mean values derived by PC-MR and US were similar ( p  > 0.05). Post-operatively, the intra-luminal signal intensity was hypo-intense at the anastomosis site using ToF and MEDIC. At the same site the outer boundary of the vessel was consistently lost on ToF, but remained clearly delineated on the MEDIC images. Discussion With the exception of ToF, the MRI data demonstrated excellent agreement with US for measurements of vessel geometry and flow velocity. Further, the ability to clearly delineate the post-surgery vessel edges with MEDIC MRI suggests that the technique may be useful for surveillance after AVF creation or for patient-specific modelling studies.