Multifocal PVNS in a child – followed over 25 years

• Published in: Skeletal radiology Vol. 35; no. 7; pp. 539 - 542
• Main Authors: Mukhopadhyay, Kausik, Smith, M., Hughes, P. M.
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.07.2006; Springer Nature B.V
• Subjects: Biological and medical sciences; Child, Preschool; Disease Progression; Diseases of the osteoarticular system; Follow-Up Studies; Humans; Inflammatory joint diseases; Joints; Magnetic Resonance Imaging; Medical sciences; Synovitis, Pigmented Villonodular - diagnosis; Synovitis, Pigmented Villonodular - pathology; Time; Human; Knee; Multiple; MRI; Multiple joints; Diseases of the osteoarticular system; Inflammatory joint disease; Joint; Nuclear magnetic resonance imaging; Pigmented villonodular synovitis; Chronic; Medical imagery; Child; Age; Bibliographic review
• ISSN: 0364-2348; 1432-2161
• DOI: 10.1007/s00256-005-0013-0

Pigmented villonodular synovitis (PVNS) is a rare disorder of unknown aetiology, characterised by a destructive fibrohistiocytic proliferation with production of villous and nodular protrusions. The disease is commonly monoarticular, and involves the knee in 80% of cases. Occurrence in a child and involvement of multiple joints are extremely unusual. We present a case of multiple joint PVNS in a patient who first presented at the age of five and was subsequently followed up for over twenty-five years. The literature on the subject is briefly reviewed.