Perspectives on Bovine Milk-Derived Extracellular Vesicles for Therapeutic Applications in Gut Health

Extracellular vesicles (EVs) are nanosized vesicles secreted from cells into the extracellular environment and are composed of a lipid bilayer that contains cargos with biological activity, such as lipids, proteins, mRNAs, and noncoding microRNAs (miRNAs). Due to their biological activity and their...

Full description

Saved in:
Bibliographic Details
Published inFood science of animal resources Vol. 42; no. 2; pp. 197 - 209
Main Authors Mun, Daye, Oh, Sangnam, Kim, Younghoon
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Society for Food Science of Animal Resources 01.03.2022
한국축산식품학회
Subjects
Online AccessGet full text
ISSN2636-0772
2636-0780
2636-0780
DOI10.5851/kosfa.2022.e8

Cover

More Information
Summary:Extracellular vesicles (EVs) are nanosized vesicles secreted from cells into the extracellular environment and are composed of a lipid bilayer that contains cargos with biological activity, such as lipids, proteins, mRNAs, and noncoding microRNAs (miRNAs). Due to their biological activity and their role in cell-to-cell communication, interest in EVs is rapidly increasing. Bovine milk is a food consumed by people of all ages around the world that contains not only a significant amount of nutrients but also EVs. Milk-derived EVs also exhibit biological activity similar to other source-derived EVs, and studies on bovine milk EVs have been conducted in various research fields regarding sufficient milk production. In particular, not only are the effects of milk EVs themselves being studied, but the possibility of using them as drug carriers or biomarkers is also being studied. In this review, the characteristics and cargo of milk EVs are summarized, as well as their uptake and stability, efficacy and biological effects as carriers, and future research directions are presented.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:2636-0772
2636-0780
2636-0780
DOI:10.5851/kosfa.2022.e8