A rare case of late chromophobe RCC metastasis with indolent course

Renal cell carcinoma (RCC) is the predominant solid lesion of the kidney. Among the various subtypes of RCC, chromophobe RCC (chRCC) is relatively rare, and it is characterized by an indolent clinical course and a favourable prognosis. We present a rare case of a 40-year-old patient who developed a...

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Published inUrology case reports Vol. 63; p. 103180
Main Authors Anastasiou, Periklis, Douroumis, Konstantinos, Panagopoulos, Panagiotis, Katsikatsos, Panagiotis, Kalfountzos, Christos, Davakis, Spyridon, Anastasiou, Ioannis
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.2025
Elsevier
Subjects
Chromophobe
Metastasectomy
Renal cell carcinoma
Retroperitoneum
Retroperitoneum
Metastasectomy
Renal cell carcinoma
Chromophobe
Online AccessGet full text
ISSN2214-4420
2214-4420
DOI10.1016/j.eucr.2025.103180

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Summary:Renal cell carcinoma (RCC) is the predominant solid lesion of the kidney. Among the various subtypes of RCC, chromophobe RCC (chRCC) is relatively rare, and it is characterized by an indolent clinical course and a favourable prognosis. We present a rare case of a 40-year-old patient who developed a retroperitoneal metastasis four years after undergoing radical nephrectomy for chRCC. The patient was under surveillance for another six years before surgical excision of the recurrence was performed. This case underscores the potential for late recurrence in chRCC and highlights the importance of long-term surveillance, even in patients with an initially favourable prognosis.
Bibliography:ObjectType-Case Study-2
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ISSN:2214-4420
2214-4420
DOI:10.1016/j.eucr.2025.103180