Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation

• Published in: The New England journal of medicine Vol. 389; no. 18; pp. 1660 - 1671
• Main Authors: Reddy, Vivek Y., Gerstenfeld, Edward P., Natale, Andrea, Whang, William, Cuoco, Frank A., Patel, Chinmay, Mountantonakis, Stavros E., Gibson, Douglas N., Harding, John D., Ellis, Christopher R., Ellenbogen, Kenneth A., DeLurgio, David B., Osorio, Jose, Achyutha, Anitha B., Schneider, Christopher W., Mugglin, Andrew S., Albrecht, Elizabeth M., Stein, Kenneth M., Lehmann, John W., Mansour, Moussa
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 02.11.2023
• Subjects: Ablation; Adverse events; Arrhythmias; Atrial Fibrillation - classification; Atrial Fibrillation - surgery; Bayes Theorem; Bayesian analysis; Cardiac arrhythmia; Cardiology; Cardiology General; Catheter Ablation - adverse effects; Catheter Ablation - methods; Catheters; Defibrillators; Enrollments; Fibrillation; Fistula; Humans; Hypotheses; Hypothesis testing; Magnetic resonance imaging; Myocardium; Pacemakers; Patient safety; Probability; Pulmonary Veins - surgery; Recurrence; Safety; Single-Blind Method; Software; Statistical analysis; Success; Tachyarrhythmia; Tachycardia - etiology; Treatment Outcome
• ISSN: 0028-4793; 1533-4406; 1533-4406
• DOI: 10.1056/NEJMoa2307291

In a randomized trial involving patients with paroxysmal atrial fibrillation, pulsed field ablation was noninferior to thermal ablation with respect to freedom from a composite of procedural and arrhythmia events at 1 year.