Spatial deformation of nanocellulose hydrogel enhances SERS

• Published in: Biochip journal Vol. 7; no. 3; pp. 234 - 241
• Main Authors: Park, Minsung, Chang, Hyejin, Jeong, Dae Hong, Hyun, Jinho
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2013; Springer Nature B.V; 한국바이오칩학회
• Subjects: Biomedical Engineering and Bioengineering; Biotechnology; Cellulose; Chemistry; Chemistry and Materials Science; Gold; Hydrogels; Nanoparticles; Original Article; Phenylacetic acid; Raman spectroscopy; Substrates; 생물공학; Three-dimensional substrate; Bacterial cellulose; Hydrogel; Gold nanoparticles; SERS hot spot; Surface-enhanced Raman spectroscopy
• ISSN: 1976-0280; 2092-7843
• DOI: 10.1007/s13206-013-7306-5

Bacterial cellulose hydrogels containing gold nanoparticles (AuNPs-BC) were prepared using a cost-effective and environment-friendly in situ synthesis method. Well-dispersed AuNPs were grown on the nanofiber surface of the BC hydrogel, forming substrates of surface-enhanced Raman spectroscopy (SERS). Increases in SERS-active sites in the AuNPs-BC hydrogel caused the enhancement of SERS intensity. The enhancement in SERS intensity of 4-fluorobenzenethiol and phenylacetic acid (PAA), used as test analytes, was compared with spatially-un-deformed AuNPs-BC hydrogels, as well as spatially-deformed AuNPs-BC hydrogels in which the BC layers had contracted during drying. Particularly noteworthy was the detection of PAA by the simple contraction of the substrate, despite a low affinity to surface gold.