Frequency of HPA-15a and HPA-15b (Gov a/b) Human Platelet Alloantigens in the Croatian Population
Human platelet antigen (HPA) genotyping is important for epidemiological studies because the prevalence of particular HPA allotypes differs among various populations and plays a major role in the occurrence of HPA alloimmunization. In Caucasians, antibodies to HPA-1a are the most important causes of...
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| Published in | Archives of medical research Vol. 37; no. 1; pp. 172 - 174 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
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United States
Elsevier Inc
2006
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0188-4409 1873-5487 |
| DOI | 10.1016/j.arcmed.2005.06.001 |
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| Abstract | Human platelet antigen (HPA) genotyping is important for epidemiological studies because the prevalence of particular HPA allotypes differs among various populations and plays a major role in the occurrence of HPA alloimmunization. In Caucasians, antibodies to HPA-1a are the most important causes of neonatal alloimmune thrombocytopenia (NATP). Recent studies suggest that anti-HPA 15a/15b (Gov b, Gov a) might be the most likely candidate antibodies following anti-HPA-1a in inducing NATP.
In the present study, HPA-15 system genotype was determined by PCR-SSP method in 279 unrelated subjects from the Croatian population, yielding an HPA-15a and HPA-15b frequency of 0.53 and 0.47, respectively.
Retrograde testing for the presence of anti-HPA-15 antibodies by use of MAIPA in 39 frozen serum samples from serologically negative cases of clinically suspect NATP produced negative results.
The clinical role of anti-HPA-15 alloantibodies was unable to be confirmed. |
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| AbstractList | Human platelet antigen (HPA) genotyping is important for epidemiological studies because the prevalence of particular HPA allotypes differs among various populations and plays a major role in the occurrence of HPA alloimmunization. In Caucasians, antibodies to HPA-1a are the most important causes of neonatal alloimmune thrombocytopenia (NATP). Recent studies suggest that anti-HPA 15a/15b (Gov b, Gov a) might be the most likely candidate antibodies following anti-HPA-1a in inducing NATP.BACKGROUNDHuman platelet antigen (HPA) genotyping is important for epidemiological studies because the prevalence of particular HPA allotypes differs among various populations and plays a major role in the occurrence of HPA alloimmunization. In Caucasians, antibodies to HPA-1a are the most important causes of neonatal alloimmune thrombocytopenia (NATP). Recent studies suggest that anti-HPA 15a/15b (Gov b, Gov a) might be the most likely candidate antibodies following anti-HPA-1a in inducing NATP.In the present study, HPA-15 system genotype was determined by PCR-SSP method in 279 unrelated subjects from the Croatian population, yielding an HPA-15a and HPA-15b frequency of 0.53 and 0.47, respectively.METHODSIn the present study, HPA-15 system genotype was determined by PCR-SSP method in 279 unrelated subjects from the Croatian population, yielding an HPA-15a and HPA-15b frequency of 0.53 and 0.47, respectively.Retrograde testing for the presence of anti-HPA-15 antibodies by use of MAIPA in 39 frozen serum samples from serologically negative cases of clinically suspect NATP produced negative results.RESULTSRetrograde testing for the presence of anti-HPA-15 antibodies by use of MAIPA in 39 frozen serum samples from serologically negative cases of clinically suspect NATP produced negative results.The clinical role of anti-HPA-15 alloantibodies was unable to be confirmed.CONCLUSIONThe clinical role of anti-HPA-15 alloantibodies was unable to be confirmed. Human platelet antigen (HPA) genotyping is important for epidemiological studies because the prevalence of particular HPA allotypes differs among various populations and plays a major role in the occurrence of HPA alloimmunization. In Caucasians, antibodies to HPA-1a are the most important causes of neonatal alloimmune thrombocytopenia (NATP). Recent studies suggest that anti-HPA 15a/15b (Gov b, Gov a) might be the most likely candidate antibodies following anti-HPA-1a in inducing NATP. In the present study, HPA-15 system genotype was determined by PCR-SSP method in 279 unrelated subjects from the Croatian population, yielding an HPA-15a and HPA-15b frequency of 0.53 and 0.47, respectively. Retrograde testing for the presence of anti-HPA-15 antibodies by use of MAIPA in 39 frozen serum samples from serologically negative cases of clinically suspect NATP produced negative results. The clinical role of anti-HPA-15 alloantibodies was unable to be confirmed. |
| Author | Hundric-Haspl, Zeljka Tomicic, Maja Drazic, Vesna Bingulac-Popovic, Jasna |
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| CitedBy_id | crossref_primary_10_1111_j_1365_3148_2009_00971_x crossref_primary_10_1111_j_1751_553X_2011_01358_x crossref_primary_10_1111_j_1751_553X_2011_01344_x crossref_primary_10_1111_jog_15257 crossref_primary_10_1111_j_1365_3148_2010_01020_x crossref_primary_10_1159_000514487 crossref_primary_10_1111_j_1399_0039_2010_01503_x crossref_primary_10_1111_trf_12455 crossref_primary_10_1111_trf_16845 |
| Cites_doi | 10.1111/j.1479-828X.2001.tb01293.x 10.1046/j.1537-2995.1997.37897424405.x 10.1046/j.1537-2995.2003.00354.x 10.1046/j.1423-0410.2003.00331.x 10.1046/j.1365-2141.2000.02170.x 10.1046/j.1423-0410.2002.00187.x 10.1182/blood.V70.6.1722.1722 10.1182/blood.V99.5.1692 |
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| Keywords | Antiplatelet antibodies Croatian population Neonatal alloimmune thrombocytopenia Human platelet antigens 15a/b frequency Monoclonal antibody-immobilization of platelet antigens |
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| References | Berry, Murphy, Smith, Ranasinghe, Finberg, Walton, Brown, Navarrete, Metcalfe, Ouwehand (bib5) 2000; 110 Hurd, Cavanagh, Schuh, Ouwehand, Metcalfe (bib2) 2002; 83 Spencer, Burrows (bib3) 2001; 41 Randen, Sørensen, Killie, Kjeldsen-Kragh (bib9) 2003; 43 Kiefel, Santoso, Weisheit, Mueller Eckhardt (bib8) 1987; 70 Metcalfe, Watkins, Ouwehand, Kaplan, Newman, Kekomaki, De Haas, Aster, Shibata, Smith, Kiefel, Santoso (bib7) 2003; 85 Schuh, Watkins, Nguyen, Harmer, Lin, Prosper, Campbell, Sutherland, Metcalfe, Horsfall, Ouwehand (bib6) 2002; 99 Kickler (bib1) 2000 Bordin, Kelton, Warner, Smith, Denomme, Warkentin, McGarath, Michinton, Hayward (bib4) 1997; 37 Schuh (10.1016/j.arcmed.2005.06.001_bib6) 2002; 99 Metcalfe (10.1016/j.arcmed.2005.06.001_bib7) 2003; 85 Kickler (10.1016/j.arcmed.2005.06.001_bib1) 2000 Spencer (10.1016/j.arcmed.2005.06.001_bib3) 2001; 41 Berry (10.1016/j.arcmed.2005.06.001_bib5) 2000; 110 Bordin (10.1016/j.arcmed.2005.06.001_bib4) 1997; 37 Kiefel (10.1016/j.arcmed.2005.06.001_bib8) 1987; 70 Randen (10.1016/j.arcmed.2005.06.001_bib9) 2003; 43 Hurd (10.1016/j.arcmed.2005.06.001_bib2) 2002; 83 |
| References_xml | – volume: 83 start-page: 1 year: 2002 end-page: 12 ident: bib2 article-title: Genotyping for platelet-specific antigens: techniques for detection of single nucleotide polymorphisms publication-title: Vox Sang – volume: 41 start-page: 45 year: 2001 end-page: 55 ident: bib3 article-title: Feto-maternal alloimmune thrombocytopenia: a literature review and statistical analysis publication-title: Aust N Z J Obstet Gynaecol – volume: 110 start-page: 735 year: 2000 end-page: 742 ident: bib5 article-title: Detection of Gov system antibodies by MAIPA reveals an immunogenicity similar to the HPA-5 alloantigens publication-title: Br J Haematol – volume: 85 start-page: 240 year: 2003 end-page: 245 ident: bib7 article-title: Nomenclature of human platelet antigens publication-title: Vox Sang – volume: 37 start-page: 823 year: 1997 end-page: 828 ident: bib4 article-title: Maternal immunization to Gov publication-title: Transfusion – volume: 43 start-page: 455 year: 2003 end-page: 460 ident: bib9 article-title: Rapid and reliable genotyping of human platelet antigen (HPA)-1, -2, -3, -4, and -5 a/b and Gov a/b by melting curve analysis publication-title: Transfusion – volume: 99 start-page: 1692 year: 2002 end-page: 1698 ident: bib6 article-title: A tyrosine 703 serine polymorphism of CD109 defines the Gov platelet alloantigens publication-title: Blood – start-page: 227 year: 2000 end-page: 236 ident: bib1 article-title: Platelet immunology publication-title: Scientific Basis of Transfusion Medicine – volume: 70 start-page: 1722 year: 1987 end-page: 1726 ident: bib8 article-title: Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for detection of platelet reactive antibodies publication-title: Blood – volume: 41 start-page: 45 year: 2001 ident: 10.1016/j.arcmed.2005.06.001_bib3 article-title: Feto-maternal alloimmune thrombocytopenia: a literature review and statistical analysis publication-title: Aust N Z J Obstet Gynaecol doi: 10.1111/j.1479-828X.2001.tb01293.x – volume: 37 start-page: 823 year: 1997 ident: 10.1016/j.arcmed.2005.06.001_bib4 article-title: Maternal immunization to Gova system alloantigens on human platelets publication-title: Transfusion doi: 10.1046/j.1537-2995.1997.37897424405.x – volume: 43 start-page: 455 year: 2003 ident: 10.1016/j.arcmed.2005.06.001_bib9 article-title: Rapid and reliable genotyping of human platelet antigen (HPA)-1, -2, -3, -4, and -5 a/b and Gov a/b by melting curve analysis publication-title: Transfusion doi: 10.1046/j.1537-2995.2003.00354.x – start-page: 227 year: 2000 ident: 10.1016/j.arcmed.2005.06.001_bib1 article-title: Platelet immunology – volume: 85 start-page: 240 year: 2003 ident: 10.1016/j.arcmed.2005.06.001_bib7 article-title: Nomenclature of human platelet antigens publication-title: Vox Sang doi: 10.1046/j.1423-0410.2003.00331.x – volume: 110 start-page: 735 year: 2000 ident: 10.1016/j.arcmed.2005.06.001_bib5 article-title: Detection of Gov system antibodies by MAIPA reveals an immunogenicity similar to the HPA-5 alloantigens publication-title: Br J Haematol doi: 10.1046/j.1365-2141.2000.02170.x – volume: 83 start-page: 1 year: 2002 ident: 10.1016/j.arcmed.2005.06.001_bib2 article-title: Genotyping for platelet-specific antigens: techniques for detection of single nucleotide polymorphisms publication-title: Vox Sang doi: 10.1046/j.1423-0410.2002.00187.x – volume: 70 start-page: 1722 year: 1987 ident: 10.1016/j.arcmed.2005.06.001_bib8 article-title: Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for detection of platelet reactive antibodies publication-title: Blood doi: 10.1182/blood.V70.6.1722.1722 – volume: 99 start-page: 1692 year: 2002 ident: 10.1016/j.arcmed.2005.06.001_bib6 article-title: A tyrosine 703 serine polymorphism of CD109 defines the Gov platelet alloantigens publication-title: Blood doi: 10.1182/blood.V99.5.1692 |
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| SubjectTerms | Antigens, CD - genetics Antigens, CD - immunology Antiplatelet antibodies Autoantibodies - immunology Croatia Croatian population Female Gene Frequency GPI-Linked Proteins Human platelet antigens 15a/b frequency Humans Isoantibodies - immunology Isoantigens - genetics Isoantigens - immunology Male Monoclonal antibody-immobilization of platelet antigens Neonatal alloimmune thrombocytopenia Neoplasm Proteins - genetics Neoplasm Proteins - immunology Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational Thrombocytopenia - immunology |
| Title | Frequency of HPA-15a and HPA-15b (Gov a/b) Human Platelet Alloantigens in the Croatian Population |
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