Anterior High-Intensity Zone in Lumbar Discs: Prevalence and Association with Low Back Pain

• Published in: Pain medicine (Malden, Mass.) Vol. 21; no. 10; pp. 2111 - 2116
• Main Authors: Wang, Zi-Xuan, Hou, Zeng-Tao, Hu, You-Gu
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.10.2020
• Subjects: Age; Aged; Back pain; Health aspects; Humans; Image processing; Intervertebral Disc - diagnostic imaging; Intervertebral disk; Low back pain; Low Back Pain - diagnostic imaging; Low Back Pain - epidemiology; Lumbar Vertebrae - diagnostic imaging; Lumbosacral Region - diagnostic imaging; Magnetic Resonance Imaging; Middle Aged; Morphology; Physiological aspects; Prevalence; Retrospective Studies; Risk factors; Spatial distribution; Spine (lumbar); Statistics; Vertebrae, Lumbar; China; High-Intensity Zone; Low Back Pain; Intervertebral Disc; MRI; Anterior Annulus
• ISSN: 1526-2375; 1526-4637; 1526-4637
• DOI: 10.1093/pm/pnaa236

Abstract Objectives To explore the features of high-intensity zone (HIZ) in anterior annulus fibrosus and assess the association of anterior HIZ with low back pain (LBP). Design, Setting, and Subjects A retrospective study of 5,940 discs in 1,188 individuals was conducted. Methods Subjects’ information and LBP symptoms confirmed by an orthopedic surgeon were acquired from the medical record. Magnetic resonance (MR) image reading and analysis were performed by two experienced blinded radiologists. Results Two hundred eighty individuals exhibited 355 anterior HIZs in 355 discs. The prevalence was 23.57%; 88.45% were located in the inferior part of the annulus fibrosus. It frequently occurred in the middle and upper segments of lumbar spine, especially at L3/4 (45.63%). Of the 355 anterior HIZs, only 79 (22.25%) were consecutive-slides HIZ. Round type (63.38%) was the most common shape of anterior HIZs. The highest prevalence was found in individuals aged 60–69 years. LBP was confirmed in 141 anterior-HIZ individuals. The incidence of LBP in anterior-HIZ individuals was significantly higher than in non-HIZ subjects (50.36% vs 35.24%, χ2 = 18.314, P < 0.001). Conclusions Anterior HIZ is a lower-prevalence, age-related sign on lumbar MR images. The spatial distribution of anterior HIZ can be distinguished from posterior HIZ. The number of consecutive anterior HIZ slides might suggest fewer Dallas grade 4 anterior annular disruptions in this sample. Anterior HIZ was correlated with LBP.