Modelling microtubule patterns

The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how thi...

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Bibliographic Details
Published inNature cell biology Vol. 8; no. 11; pp. 1204 - 1211
Main Authors Karsenti, Eric, Nédélec, François, Surrey, Thomas
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.11.2006
Nature Publishing Group
Subjects
Adenosine Triphosphate - chemistry
Adenosine Triphosphate - metabolism
Algorithms
Animals
Biology
Biomedical and Life Sciences
Cancer Research
Cell Biology
Cell interaction
Cytoskeleton
Developmental Biology
Humans
Kinetics
Life Sciences
Microtubules
Microtubules - chemistry
Microtubules - metabolism
Models, Biological
Models, Chemical
Pattern formation (Developmental biology)
Physical properties
Physiological aspects
Protein Binding
review-article
Stem Cells
Tubulin - chemistry
Tubulin - metabolism
Online AccessGet full text
ISSN1465-7392
1476-4679
DOI10.1038/ncb1498

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Summary:The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how this led to the beginning of an understanding of dynamic cellular patterns that have precise functions.
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ISSN:1465-7392
1476-4679
DOI:10.1038/ncb1498