An Updated Review of Emerging Sources of Selenium in Weaned Piglet Nutrition

• Published in: Animals (Basel) Vol. 14; no. 17; p. 2599
• Main Authors: Zhou, Wenyue, Yang, Zheng, Han, Jiajun, Chen, Xingping, Zou, Tiande, You, Jinming, Chen, Jun
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.09.2024
• Subjects: anti-inflammation; antioxidant; Antioxidants; diet; emerging selenium sources; enterotoxigenic Escherichia coli; Escherichia infections; heat stress; Hogs; Inflammation; Liver; mycotoxins; Nanoparticles; Nutrition; Oxidative stress; piglets; Probiotics; Selenium; selenoproteins; Sodium; sodium selenite; stress challenges; weaned piglets; Weaning; yeasts; antioxidant; anti-inflammation; stress challenges; emerging selenium sources; weaned piglets
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani14172599

The antioxidant and immune systems of weaned piglets are not fully mature and are also subjected to serious stress challenges related to oxidative stress and inflammation. Selenium (Se) is an essential element for pigs, with documented roles encompassing antioxidative and anti-inflammatory properties via selenoproteins. Sodium selenite and Se-enriched yeast are commonly acknowledged as conventional sources of Se for piglets. In the past decade, several novel Se sources have emerged in the field of weaned piglet nutrition. In this review, we will initially outline the historical timeline of Se sources as reported in weaned piglet nutrition. Afterwards, our attention will turn towards the nutritional regulation of Se sources in relation to the antioxidant and anti-inflammatory aspects of healthy weaned piglets. Ultimately, we will provide a detailed review highlighting the potential of emerging Se sources in alleviating various adverse effects of stress challenges faced by weaned piglets. These challenges include oxidative stress, enterotoxigenic Escherichia coli infection, lipopolysaccharide-induced inflammation, heat stress, and exposure to feed mycotoxins. The output of this review will emphasize the fundamental importance of incorporating emerging Se sources in the diet of weaned piglets.