Description of a Cohort of Type 1 Diabetes Patients: Analysis of Comorbidities, Prevalence of Complications and Risk of Hypoglycemia

Background: Despite major medical advances, Type 1 Diabetes (T1D) patients still have greater morbimortality than the general population. Our aim was to describe our cohort of T1D patients and identify potential risk factors susceptible to prevention strategies. Methods: Cross-sectional, observation...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical medicine Vol. 11; no. 4; p. 1039
Main Authors Martínez-Ortega, Antonio J., Muñoz-Gómez, Cristina, Gros-Herguido, Noelia, Remón-Ruiz, Pablo Jesús, Acosta-Delgado, Domingo, Losada-Viñau, Fernando, Pumar-López, Alfonso, Mangas-Cruz, Miguel Ángel, González-Navarro, Irene, López-Gallardo, Gema, Bellido, Virginia, Soto-Moreno, Alfonso Manuel
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 17.02.2022
MDPI
Subjects
Online AccessGet full text
ISSN2077-0383
2077-0383
DOI10.3390/jcm11041039

Cover

More Information
Summary:Background: Despite major medical advances, Type 1 Diabetes (T1D) patients still have greater morbimortality than the general population. Our aim was to describe our cohort of T1D patients and identify potential risk factors susceptible to prevention strategies. Methods: Cross-sectional, observational study, including T1D patients treated at our center, from 1 March 2017 to 31 March 2020. Inclusion criteria: T1D, age > 14 years and signed informed consent. Exclusion criteria: diabetes other than T1D, age < 14 years and/or refusal to participate. Results: Study population n = 2181 (49.8% females, median age at enrollment 41 years, median HbA1c 7.7%; 38.24% had at least one comorbidity). Roughly 7.45% had severe hypoglycemia (SH) within the prior year. Macro/microvascular complications were present in 42.09% (5.83% and 41.14%, respectively). The most frequent microvascular complication was diabetic retinopathy (38.02%), and coronary disease (3.21%) was the most frequent macrovascular complication. The risk of complications was higher in males than in females, mainly macrovascular. Patients with SH had a higher risk of complications (OR 1.42; 1.43 in males versus 1.42 in females). Conclusions: Our T1D population is similar to other T1D populations. We should minimize the risk of SH, and male patients should perhaps be treated more aggressively regarding cardiovascular risk factors.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11041039