Excessive laboratory monitoring to prevent adolescent’s refeeding syndrome: opportunities for enhancement

• Published in: Eating and weight disorders Vol. 25; no. 4; pp. 1021 - 1027
• Main Authors: Ghaddar, Rola, Chartrand, Jessica, Benomar, Anass, Jamoulle, Olivier, Taddeo, Danielle, Frappier, Jean-Yves, Stheneur, Chantal
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2020; Springer Nature B.V; Springer Verlag
• Subjects: Age; Anorexia; Bulimia; Eating disorders; Ecology, environment; Electrolytes; Health; Hospitalization; Laboratories; Life Sciences; Malnutrition; Meals; Medicine; Medicine & Public Health; Mortality; Obesity; Original Article; Patients; Pediatrics; Phosphorus; Potassium; Psychiatry; Studies; Teenagers; Weight control; Young adults; Electrolytes; Anorexia nervosa; Eating disorder; Refeeding syndrome
• ISSN: 1590-1262; 1124-4909; 1590-1262
• DOI: 10.1007/s40519-019-00723-7

Purpose Anorexia nervosa (AN) is a complex medical condition affecting mainly adolescents and young adults. To monitor and prevent refeeding syndrome, current guidelines recommend daily laboratory testing in the first week of hospitalization and 2–3 times/week for the following 3 weeks. The aims of this study were to determine the proportion of abnormal results of the blood tests done during the first week of nutritional rehabilitation in adolescents with AN, the proportion of test having led to supplementation and the cost of all these tests. Method A retrospective chart review of admissions for eating disorders between May 2014 and May 2015 in a tertiary Pediatric University Hospital center was performed. Patients were included if they were younger than 18 years, admitted for protocol-based refeeding and met criteria for AN (DSM 5). Results Among the 99 hospitalizations included in the study, the mean age was 14.6 years (± 1.7), with a female predominance (97%). The mean admission BMI was 15.3 ± 2 kg/m 2 ( Z -score − 2.6 ± 1.4). The mean length of hospitalization was 40.3 days ± 21.8. Of the 1289 laboratory tests performed, only 1.5% revealed abnormal values and 0.85% led to supplementation. No critical value was identified. The total cost for the tests performed was 148,926.80 CAD$, 1504$/admitted patient, instead of 3890$/admitted patient had we followed the recommendations. Conclusion More precise criteria should be developed regarding the frequency of laboratory tests needed to monitor and prevent refeeding syndrome. At present, the recommendations could lead to unnecessary testing and expenses. Level of evidence Level IV: Dramatic results in uncontrolled trials.