Sparse Common Feature Analysis for Detection of Interictal Epileptiform Discharges From Concurrent Scalp EEG

• Published in: IEEE access Vol. 10; pp. 49892 - 49904
• Main Authors: Abdi-Sargezeh, Bahman, Valentin, Antonio, Alarcon, Gonzalo, Sanei, Saeid
• Format: Journal Article
• Language: English
• Published: Piscataway IEEE 2022; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Algorithms; Biomarkers; Brain modeling; Classification; Common feature analysis; Discharge; Electrodes; Electroencephalography; Epilepsy; Feature extraction; IED detection; interictal epileptiform discharges; intracranial and scalp EEGs; Recording; Scalp; sparsity; Tensors; Waveforms
• ISSN: 2169-3536; 2169-3536
• DOI: 10.1109/ACCESS.2022.3167433

Temporal interictal epileptiform discharges (IEDs) are often invisible in the scalp EEG (sEEG). However, due to within-electrode temporal correlation and between-electrode spatial correlation, they still have their signatures in the sEEG. Therefore, it is expected to have some common spatial and temporal features among the IEDs. In this paper, we first present a novel method, called common feature analysis (CFA)-based method, for IED detection via an existing common orthogonal basis extraction (COBE) algorithm. In the second approach, we benefit from the sparsity of IED waveforms in developing a new algorithm, namely sparse COBE, and based on that, a sparse CFA (SCFA)-based method for IED detection. The proposed CFA and SCFA models are compared with two state-of-the-art IED detection methods. Two types of approaches, namely within- and between-subject classification approaches, are employed for evaluating the methods. SCFA outperforms the others and achieves the accuracy values of 75.1% and 67.8% using within- and between-subject classification approaches, respectively. This enables the proposed techniques to capture the intracranial biomarkers of epilepsy and ameliorate the performance of a classifier in automatically detecting the scalp-invisible IEDs from sEEG.